孤立的肾上腺皮质细胞：垂体切除术后对促肾上腺皮质激素的超敏反应。
Isolated adrenal cortex cells: hypersensitivity to adrenocorticotropic hormone after hypophysectomy.
作者信息
Sayers G, Beall R J
出版信息
Science. 1973 Mar 30;179(4080):1330-1. doi: 10.1126/science.179.4080.1330.
PMID:4346969
Abstract
Cells from the adrenals of hypophysectomized rats (up to 28 days after operation) require less adrenocorticotropic hormone to induce one-half maximal rate of production of 3',5'-adenosine monophosphate than do cells from the adrenals of intact rats. A corresponding increase in sensitivity is reflected in the steroidogenic response to adrenocorticotropic hormone up to 2 days after hypophysectomy.
摘要
垂体切除大鼠肾上腺的细胞（术后长达28天），与正常大鼠肾上腺细胞相比，诱导3',5'-腺苷单磷酸产生速率达到最大值一半所需的促肾上腺皮质激素更少。垂体切除术后2天内，对促肾上腺皮质激素的类固醇生成反应体现出相应的敏感性增加。
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