人类肾上腺皮质中一种新的含晶体细胞。
A new crystal-containing cell in human adrenal cortex.
作者信息
Magalhàes M C
出版信息
J Cell Biol. 1972 Oct;55(1):126-33. doi: 10.1083/jcb.55.1.126.
Abstract
Electron microscope examination of the adrenal cortex from three male human subjects revealed a special type of cell occurring in periendothelial spaces, in all adrenal cortex zones. It is a clear, spindle-shaped cell the principal cytoplasmic features of which are crystalline inclusions with a structure similar to that of the Reinke crystals of human testicular interstitial cells and an abundance of microfilaments. Enzymatic digestions with pronase, pepsin, and ribonuclease were performed, and no digestion of the crystals was obtained. The crystals had no peroxidase or acid phosphatase activities. This cell appears to be exclusive to human males and it may be related to adrenal androgen secretion.
摘要
对三名男性人类受试者的肾上腺皮质进行电子显微镜检查发现，在肾上腺皮质的所有区域，一种特殊类型的细胞出现在血管周间隙中。它是一种透明的梭形细胞，其主要细胞质特征是含有与人类睾丸间质细胞的雷氏晶体结构相似的晶体包涵体以及大量微丝。用链霉蛋白酶、胃蛋白酶和核糖核酸酶进行了酶消化，未获得晶体的消化结果。这些晶体没有过氧化物酶或酸性磷酸酶活性。这种细胞似乎是人类男性所特有的，可能与肾上腺雄激素分泌有关。
相似文献
1
A new crystal-containing cell in human adrenal cortex.人类肾上腺皮质中一种新的含晶体细胞。
J Cell Biol. 1972 Oct;55(1):126-33. doi: 10.1083/jcb.55.1.126.
2
Secretion and endocytosis in insulin-stimulated rat adrenal medulla cells.胰岛素刺激的大鼠肾上腺髓质细胞中的分泌与胞吞作用。
J Cell Biol. 1973 Feb;56(2):540-58. doi: 10.1083/jcb.56.2.540.
3
Differential enzymatic digestion of cytoplasmic components of keratinocytes: electron microscopic observations.角质形成细胞胞质成分的差异酶消化：电子显微镜观察
J Ultrastruct Res. 1971 Aug;36(3):437-54. doi: 10.1016/s0022-5320(71)80116-8.
4
Epidermal globular nuclear inclusions: an ultrastructural cytochemical study.
J Ultrastruct Res. 1976 Jul;56(1):15-20. doi: 10.1016/s0022-5320(76)80136-0.
5
Morphology and microanatomy of the adrenal cortex of the coyote.郊狼肾上腺皮质的形态学与显微解剖学
Anat Rec. 1971 Apr;169(4):627-36. doi: 10.1002/ar.1091690403.
6
[Double reaction (acid phosphatase and peroxidase) in maturing mice neutrophils. Electron-cytochemical study].[成熟小鼠中性粒细胞中的双重反应（酸性磷酸酶和过氧化物酶）。电子细胞化学研究]
Izv Akad Nauk SSSR Biol. 1972 Jan-Feb;1:135-41.
7
The origin and composition of peroxidase-positive granules in cysteamine-treated astrocytes in culture.
Brain Res. 1994 Jan 7;633(1-2):9-20. doi: 10.1016/0006-8993(94)91516-4.
8
[Cytochemical studies of primary granules in rat neutrophils: an electron microscope study].[大鼠中性粒细胞中初级颗粒的细胞化学研究：一项电子显微镜研究]
Acta Haematol Pol. 1976;7(4):311-9.
9
10
Cytochemical studies of lysosomes, golgi apparatus and endoplasmic reticulum in secretion and protein uptake by adrenal medulla cells of the rat.大鼠肾上腺髓质细胞分泌及蛋白质摄取过程中溶酶体、高尔基体和内质网的细胞化学研究
J Histochem Cytochem. 1968 May;16(5):320-36. doi: 10.1177/16.5.320.
引用本文的文献
1
A New Leydig Cell-Exclusive Cre Line Allows Lineage Tracing of Fetal and Adult Leydig Cell Populations in the Mouse.一种新的仅在睾丸间质细胞表达的Cre品系可用于对小鼠胎儿和成体睾丸间质细胞群体进行谱系追踪。
Endocrinology. 2025 Jan 6;166(2). doi: 10.1210/endocr/bqaf012.
2
Reinke's crystals in perivascular and peritubular Leydig cells of men with non-obstructive and obstructive azoospermia: a retrospective case control study.非梗阻性和梗阻性无精子症男性血管周围和肾小管周围Leydig细胞中的Reinke晶体：一项回顾性病例对照研究
Croat Med J. 2019 Apr 30;60(2):158-165. doi: 10.3325/cmj.2019.60.158.
3
Immunophenotypic differences between neoplastic and non-neoplastic androgen-producing cells containing and lacking Reinke crystals.含有和缺乏雷氏结晶的肿瘤性和非肿瘤性雄激素产生细胞之间的免疫表型差异。
Virchows Arch. 2016 Dec;469(6):679-686. doi: 10.1007/s00428-016-2028-4. Epub 2016 Oct 1.
4
Animal models of adrenocortical tumorigenesis.肾上腺皮质肿瘤发生的动物模型。
Mol Cell Endocrinol. 2012 Mar 31;351(1):78-86. doi: 10.1016/j.mce.2011.09.045. Epub 2011 Nov 11.
5
Visualization of Reinke's crystals in normal and cryptorchid testis.正常和隐睾睾丸中 Reinke 晶体的可视化。
Histochem Cell Biol. 2011 Feb;135(2):215-28. doi: 10.1007/s00418-011-0782-6. Epub 2011 Feb 2.
6
Catalase-like crystals in parathyroid gland cells of Rana temporaria L.
Cell Tissue Res. 1974;153(2):167-73. doi: 10.1007/BF00226605.
7
Ultrastructure of Leydig cell paracrystalline inclusions, possibly related to Reinke crystals, in the normal human testis.正常人类睾丸中可能与雷氏晶体相关的睾丸间质细胞类晶体包涵体的超微结构。
Z Zellforsch Mikrosk Anat. 1973 Aug 27;142(1):13-26. doi: 10.1007/BF00306701.
8
Crystalloid formation in Leydig cells of rats (Rattus fuscipes). An ultrastructural and hormonal study.
Cell Tissue Res. 1986;245(1):91-100. doi: 10.1007/BF00218090.
9
Stereological analysis of Reinke's crystals in human Leydig cells.
Virchows Arch A Pathol Anat Histol. 1978 Oct 18;380(1):1-9. doi: 10.1007/BF00432889.
本文引用的文献
1
A SIMPLIFIED LEAD CITRATE STAIN FOR USE IN ELECTRON MICROSCOPY.一种用于电子显微镜的简化柠檬酸铅染色法。
J Cell Biol. 1965 May;25(2):407-8. doi: 10.1083/jcb.25.2.407.
2
LYTIC ACTIVITIES IN RENAL PROTEIN ABSORPTION DROPLETS. AN ELECTRON MICROSCOPICAL CYTOCHEMICAL STUDY.肾蛋白吸收液滴中的溶解活性。一项电子显微镜细胞化学研究。
J Cell Biol. 1964 Dec;23(3):519-52. doi: 10.1083/jcb.23.3.519.
3
[Electron microscope studies on spheroid bodies in the human adrenal cortex].
Z Zellforsch Mikrosk Anat. 1962;57:827-37.
4
Improvements in epoxy resin embedding methods.环氧树脂包埋方法的改进。
J Biophys Biochem Cytol. 1961 Feb;9(2):409-14. doi: 10.1083/jcb.9.2.409.
5
Embedding in epoxy resins for ultrathin sectioning in electron microscopy.嵌入环氧树脂用于电子显微镜超薄切片。
Stain Technol. 1960 Nov;35:313-23. doi: 10.3109/10520296009114754.
6
The ultrastructure of the human adrenal cortex before and after stimulation with ACTH.
J Pathol Bacteriol. 1961 Jan;81:101-6. doi: 10.1002/path.1700810112.
7
Observations on the fine structure of the adrenal cortex of man.关于人类肾上腺皮质精细结构的观察
Lab Invest. 1967 Oct;17(4):355-70.
8
Distribution of peroxisomes (microbodies) in the nephron of the rat: a cytochemical study.大鼠肾单位中过氧化物酶体（微体）的分布：细胞化学研究
J Cell Biol. 1969 Aug;42(2):501-18. doi: 10.1083/jcb.42.2.501.
9
The crystal structure of bovine liver catalase: a combined study by x-ray diffraction and electron microscopy.
J Mol Biol. 1967 Dec 14;30(2):323-7. doi: 10.1016/s0022-2836(67)80042-1.
10
Ultrastructure of the adrenal cortex in Cushing's disease in children.
Hum Pathol. 1970 Dec;1(4):595-614. doi: 10.1016/s0046-8177(70)80059-4.
Zotero 插件