Mohandessan M, Fetkenhour C, O'Grady R
Ann Ophthalmol. 1979 Feb;11(2):189-92.
A white woman with unilateral nevus of Ota presented with visual loss and an intraocular mass resembling a choroidal melanoma. Indirect ophthalmoscopy, fluorescein angiography, ultrasonography, and radioactive phosphorus uptake corroborated the clinical impression and surgery was advised. Following enucleation, the specimen was examined with light microscopy, which revealed a mixed cell type malignant melanoma of the choroid. Electron microscopy disclosed the presence of premelanosomes in the episclera, indicating that the episcleral pigmentation is a result of melanocytic evolution. This paper represents the tenth report in the literature of choroidal melanoma occurring in a patient with nevus of Ota, and the first electron-microscopic study of an eye with this association of lesions.
一名患有单侧太田痣的白人女性出现视力丧失，眼内有一肿块，类似脉络膜黑色素瘤。间接检眼镜检查、荧光素血管造影、超声检查及放射性磷摄取检查均证实了临床诊断，并建议进行手术。眼球摘除术后，对标本进行光学显微镜检查，结果显示为脉络膜混合细胞型恶性黑色素瘤。电子显微镜检查发现巩膜上存在前黑素小体，表明巩膜色素沉着是黑素细胞演变的结果。本文是文献中关于太田痣患者发生脉络膜黑色素瘤的第十篇报告，也是对有这种病变关联的眼睛进行的首次电子显微镜研究。
