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5 ppm一氧化氮暴露后家兔肺的超微结构变化。

Ultrastructural changes of the rabbit lung after a 5 ppm nitric oxide exposure.

作者信息

Hugod C

出版信息

Arch Environ Health. 1979 Jan-Feb;34(1):12-7. doi: 10.1080/00039896.1979.10667360.

DOI:10.1080/00039896.1979.10667360
PMID:434920
Abstract

Four male rabbits were continuously exposed to 5 ppm nitric oxide for 14 days. Four rabbits served as controls. Specimens from pulmonary arterioles and alveolar tissue were examined by light and transmission electron microscopy. The most conspicuous findings were fluid-containing vacuoles inside the arteriolar endothelial cells and/or in the intercellular junctions. Thickening of the alveolo-capillary membrane due to accumulation of edema fluid in the interstitial space was also observed.

摘要

将四只雄性兔子连续14天暴露于5 ppm的一氧化氮环境中。另外四只兔子作为对照。通过光学显微镜和透射电子显微镜对肺小动脉和肺泡组织的样本进行检查。最显著的发现是小动脉内皮细胞内和/或细胞间连接处有含液泡。还观察到由于间质空间中水肿液的积聚导致肺泡-毛细血管膜增厚。

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引用本文的文献

1
Effect of exposure to 43 ppm nitric oxide and 3.6 ppm nitrogen dioxide on rabbit lung. A light and electron microscopic study.暴露于43 ppm一氧化氮和3.6 ppm二氧化氮对兔肺的影响。一项光镜和电镜研究。
Int Arch Occup Environ Health. 1979 Jan 15;42(3-4):159-67. doi: 10.1007/BF00377770.
2
Effect of exposure to 0.5 ppm hydrogen cyanide singly or combined with 200 ppm carbon monoxide and/or 5 ppm nitric oxide on coronary arteries, aorta, pulmonary artery, and lungs in the rabbit.
Int Arch Occup Environ Health. 1979 Aug;44(1):13-23. doi: 10.1007/BF00381205.