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性别和膳食钙对大鼠肠道镉吸收的影响。

Influence of sex and dietary calcium on intestinal cadmium absorption in rats.

作者信息

Kello D, Dekanić D, Kostial K

出版信息

Arch Environ Health. 1979 Jan-Feb;34(1):30-3. doi: 10.1080/00039896.1979.10667363.

DOI:10.1080/00039896.1979.10667363
PMID:434923
Abstract

The influence of sex and dietary calcium on whole-body retention of orally administered 115mCdCl2 has a half-life of 43 days, distinguishing it from 115Cd of half-life 2.3 days was studied in one-year-old control and gonadectomized male and female rats. Gonadectomy was performed at the age of four months. Each of the four experimental groups was divided into three subgroups that were fed rat food with a different calcium content (2.4, 0.7, and 0.3% Ca) throughout the experiment. Regardless of sex and gonadectomy the mean percent values of 115mCd retention in the whole body decreased with increasing dietary calcium level. Male rats retained less cadmium than all other experimental groups of animals. These data clearly point out that sex and diet might influence the level of ingested cadmium in the body.

摘要

研究了性别和膳食钙对口服115mCdCl2全身潴留的影响,其半衰期为43天,这使其与半衰期为2.3天的115Cd有所区别。实验对象为一岁的对照大鼠以及去势的雄性和雌性大鼠。在四个月大时进行去势手术。四个实验组中的每组又分为三个亚组,在整个实验过程中分别喂食钙含量不同(2.4%、0.7%和0.3%钙)的大鼠食物。无论性别和去势情况如何,全身115mCd潴留的平均百分比值均随着膳食钙水平的升高而降低。雄性大鼠体内镉的潴留量低于所有其他实验组动物。这些数据清楚地表明,性别和饮食可能会影响体内摄入镉的水平。

相似文献

1
Influence of sex and dietary calcium on intestinal cadmium absorption in rats.性别和膳食钙对大鼠肠道镉吸收的影响。
Arch Environ Health. 1979 Jan-Feb;34(1):30-3. doi: 10.1080/00039896.1979.10667363.
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Effect of age and diet on renal cadmium retention in rats.年龄和饮食对大鼠肾脏镉潴留的影响。
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Effect of dietary calcium intake and meal calcium content on calcium absorption in the rat.膳食钙摄入量和餐食钙含量对大鼠钙吸收的影响。
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Role of dietary calcium and calcium binding protein in cadmium toxicity in rats.
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[Effect of the amount of protein and calcium in the diet on cadmium chloride distribution and accumulation in the body when administered by different routes].
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Inhibition of intestinal calcium uptake by cadmium and the effect of a low calcium diet on cadmium retention.
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[Effect of the amount of protein and calcium in the diet on cadmium chloride absorption from the gastrointestinal tract].[饮食中蛋白质和钙的含量对胃肠道吸收氯化镉的影响]
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Biol Trace Elem Res. 2024 Oct 23. doi: 10.1007/s12011-024-04423-x.
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Accumulation of lead and cadmium in wild populations of the commensal rat, Rattus norvegicus.铅和镉在褐家鼠野生种群中的蓄积。
Arch Environ Contam Toxicol. 1982;11(4):407-17. doi: 10.1007/BF01056066.
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Effect of diet on tissue retention of cadmium heavily preaccumulated in rats.
饮食对镉在大鼠体内大量预先蓄积后的组织留存的影响。
Arch Environ Contam Toxicol. 1984 Sep;13(5):609-19. doi: 10.1007/BF01056340.
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Influence of essential elements on manganese intoxication.必需元素对锰中毒的影响。
Bull Environ Contam Toxicol. 1984 Jan;32(1):10-9. doi: 10.1007/BF01607459.
5
Binding of cadmium chloride and Cd-metallothionein to mucosal brush border membrane of the rat small intestinal tract.
Bull Environ Contam Toxicol. 1988 Mar;40(3):418-24. doi: 10.1007/BF01689100.