肯尼亚的类风湿性关节炎。II. 血清学观察。
Rheumatoid arthritis in Kenya. II. Serological observations.
作者信息
Houba V, Bagg L R, Hansen D P, Bowry T
出版信息
Ann Rheum Dis. 1979 Feb;38(1):26-30. doi: 10.1136/ard.38.1.26.
Sera from 48 Kenyan Africans with rheumatoid arthritis, 43 patients with other diseases, and 98 blood donors were tested for the presence of rheumatoid factor by latex fixation tests using human European, human African, and rabbit immunoglobulin, and a sheep cell haemagglutination test. In the patients with rheumatoid arthritis the frequency of rheumatoid factor was comparable to that reported in series from Europe and the USA, thus differing from the findings in West Africa. In the control patients and blood donors a high frequency of positive tests for rheumatoid factor was found; a similar result has been obtained from population studies in other African countries. Broadly similar results were obtained with each of the latex tests, and these were found to be less specific for rheumatoid arthritis than the sheep cell haemagglutination test.
采用人欧洲免疫球蛋白、人非洲免疫球蛋白和兔免疫球蛋白的乳胶凝集试验以及羊细胞血凝试验，对48名患类风湿性关节炎的肯尼亚非洲人、43名患有其他疾病的患者和98名献血者的血清进行类风湿因子检测。类风湿性关节炎患者中类风湿因子的出现频率与欧洲和美国系列报道中的频率相当，因此与西非的研究结果不同。在对照患者和献血者中，类风湿因子检测呈阳性的频率很高；在其他非洲国家的人群研究中也得到了类似结果。每种乳胶试验都得到了大致相似的结果，并且发现这些试验对类风湿性关节炎的特异性低于羊细胞血凝试验。
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