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重度类风湿关节炎中的白细胞去除术

Leucapheresis in severe rheumatoid arthritis.

作者信息

Tenenbaum J, Urowitz M B, Keystone E C, Dwosh I L, Curtis J E

出版信息

Ann Rheum Dis. 1979 Feb;38(1):40-4. doi: 10.1136/ard.38.1.40.

Abstract

Two patients with severe seropositive rheumatoid arthritis previously unresponsive to conventional therapy have been treated with leucapheresis. This technique involves continuous cell separation daily to remove primarily lymphocytes. Clinical improvement was recorded with the use of standard rheumatological measures of inflammation. It is concluded that leucapheresis may help in the management of severely active rheumatoid arthritis when conventional therapy has been unsuccessful.

摘要

两名严重血清阳性类风湿性关节炎患者此前对传统治疗无反应,现已接受白细胞去除术治疗。该技术包括每天连续进行细胞分离,主要去除淋巴细胞。使用标准的风湿病炎症指标记录到了临床改善情况。得出的结论是,当传统治疗失败时,白细胞去除术可能有助于治疗严重活动期的类风湿性关节炎。

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Cellular immunological aspects of rheumatoid arthritis.类风湿关节炎的细胞免疫学方面
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