Leimert J T, Corder M P, Skibba C A, Gingrich R D
Arch Intern Med. 1979 Apr;139(4):486-7.
The skin lesions of erythema annulare centrifugum developed in a 58-year-old woman who had Hodgkin's disease. Response of the neoplasm to vinblastine sulfate was accompanied by disappearance of the skin lesions. When therapy was discontinued, both disorders recurred, and both responded to reinstitution of vinblastine therapy. To our knowledge, this case is the first reported association of erythema annulare centrifugum and Hodgkin's disease. The cutaneous manifestation in this patient were a nonneoplastic concomitant of her neoplastic disorder.
一名患有霍奇金病的58岁女性出现了离心性环状红斑的皮肤损害。肿瘤对硫酸长春碱的反应伴随着皮肤损害的消失。当治疗中断时，两种病症均复发，且再次使用长春碱治疗后均有反应。据我们所知，该病例是首次报道的离心性环状红斑与霍奇金病的关联。该患者的皮肤表现是其肿瘤性疾病的一种非肿瘤性伴随症状。
