两亲性自旋标记物在六角形脂质相中的取向和运动
Orientation and motion of amphiphilic spin labels in hexagonal lipid phases.
作者信息
Boggs J M, Hsia J C
出版信息
Proc Natl Acad Sci U S A. 1973 May;70(5):1406-9. doi: 10.1073/pnas.70.5.1406.
Abstract
The acyl chain of spin-labeled fatty acids intercalates between the lipid hydrocarbon chains in hexagonal and micellar phases with the carboxyl group anchored at the lipid water interface. The spectra are characteristic of anisotropic motion and cannot be distinguished from the spectra of these probes in lamellar dispersions. In the hexagonal and micellar phases the molecular motion of the spin label increases as it is moved further away from the carboxyl group, similar to the behavior in the lamellar phase (Jost et al. (1971) J. Mol. Biol. 59, 77-98). The similarity in packing of the acyl chains in the hexagonal and lamellar phases suggests that localized regions of hexagonal phase are compatible with a bilayer matrix.
摘要
自旋标记脂肪酸的酰基链插入六方相和胶束相的脂质烃链之间，羧基锚定在脂质-水界面。这些光谱具有各向异性运动的特征，无法与层状分散体中这些探针的光谱区分开来。在六方相和胶束相中，自旋标记的分子运动随着其远离羧基而增加，这与层状相中的行为相似（约斯特等人，（1971年）《分子生物学杂志》59卷，77 - 98页）。六方相和层状相中酰基链堆积的相似性表明，六方相的局部区域与双层基质兼容。
相似文献
1
Orientation and motion of amphiphilic spin labels in hexagonal lipid phases.两亲性自旋标记物在六角形脂质相中的取向和运动
Proc Natl Acad Sci U S A. 1973 May;70(5):1406-9. doi: 10.1073/pnas.70.5.1406.
2
Spin label ESR and 31P-NMR studies of the cubic and inverted hexagonal phases of dimyristoylphosphatidylcholine/myristic acid (1:2, mol/mol) mixtures.二肉豆蔻酰磷脂酰胆碱/肉豆蔻酸（1:2，摩尔/摩尔）混合物立方相和反六角相的自旋标记电子自旋共振和31P核磁共振研究。
Biochim Biophys Acta. 1990 May 9;1024(1):89-94. doi: 10.1016/0005-2736(90)90211-6.
3
Transfer of stearic acids from albumin to polymer-grafted lipid containing membranes probed by spin-label electron spin resonance.通过自旋标记电子自旋共振探测硬脂酸从白蛋白到聚合物接枝脂质膜的转移。
Biophys Chem. 2005 Apr 22;114(2-3):121-7. doi: 10.1016/j.bpc.2004.11.011. Epub 2004 Nov 30.
4
Lipid chain dynamics and molecular location of diacylglycerol in hydrated binary mixtures with phosphatidylcholine: spin label ESR studies.在与磷脂酰胆碱形成的水合二元混合物中，二酰基甘油的脂链动力学和分子定位：自旋标记电子顺磁共振研究
Biochemistry. 1996 Mar 26;35(12):3831-6. doi: 10.1021/bi952688b.
5
Spin label motion in fatty acids.脂肪酸中的自旋标记运动。
Biophys J. 1973 Nov;13(11):1223-31. doi: 10.1016/S0006-3495(73)86057-6.
6
Incorporation of spin-labeled ganglioside analogues into cell and liposomal membranes.
J Biochem. 1982 May;91(5):1707-18. doi: 10.1093/oxfordjournals.jbchem.a133862.
7
Investigating fatty acids inserted into magnetically aligned phospholipid bilayers using EPR and solid-state NMR spectroscopy.利用电子顺磁共振（EPR）和固态核磁共振（NMR）光谱研究插入磁排列磷脂双层中的脂肪酸。
J Magn Reson. 2004 Jun;168(2):228-37. doi: 10.1016/j.jmr.2004.03.004.
8
Effect of independent variations in fatty acid structure and chain length on lipid polar headgroup composition in Acholeplasma laidlawii B membranes: regulation of lamellar/nonlamellar phase propensity.脂肪酸结构和链长的独立变化对莱氏无胆甾原体B膜脂质极性头部基团组成的影响：片层/非片层相倾向的调节
Biochemistry. 2003 Feb 11;42(5):1309-17. doi: 10.1021/bi026923j.
9
Lamellar and hexagonal lipid phases visualized by freeze-etching.通过冷冻蚀刻观察到的片层状和六方脂质相。
Biochim Biophys Acta. 1970;219(1):47-60. doi: 10.1016/0005-2736(70)90060-x.
10
Stearic acid spin labels in lipid bilayers: insight through atomistic simulations.脂质双层中的硬脂酸自旋标记：通过原子模拟获得的见解
J Phys Chem B. 2007 Nov 1;111(43):12447-53. doi: 10.1021/jp0746796. Epub 2007 Oct 11.
引用本文的文献
1
Bis(monoacylglycero)phosphate forms stable small lamellar vesicle structures: insights into vesicular body formation in endosomes.双（单酰甘油）磷酸形成稳定的小层状囊泡结构：对内体中囊泡体形成的见解。
Biophys J. 2009 Mar 4;96(5):1847-55. doi: 10.1016/j.bpj.2008.12.3892.
2
Order and dynamics in the lamellar L alpha and in the hexagonal HII phase. Dioleoylphosphatidylethanolamine studied with angle-resolved fluorescence depolarization.层状Lα相和六方HII相中的有序性与动力学。用角分辨荧光去极化研究二油酰磷脂酰乙醇胺。
Biophys J. 1989 May;55(5):937-47. doi: 10.1016/S0006-3495(89)82892-9.
3
Spin-label studies on rat liver and heart plasma membranes: do probe-probe interactions interfere with the measurement of membrane properties?大鼠肝脏和心脏质膜的自旋标记研究：探针 - 探针相互作用是否会干扰膜特性的测量？
J Membr Biol. 1977 Feb 24;31(1-2):131-69. doi: 10.1007/BF01869402.
4
Biophysics with nitroxyl radicals.含硝酰基自由基的生物物理学
Biophys Struct Mech. 1976 Dec 22;2(3):181-218. doi: 10.1007/BF00535367.
本文引用的文献
1
PHYSICOCHEMICAL PROPERTIES OF OX-BRAIN GANGLIOSIDES.牛脑神经节苷脂的物理化学性质
Biochem J. 1963 Aug;88(2):373-83. doi: 10.1042/bj0880373.
2
[Structure of liquid-crystalline phases of different phospholipids, monoglycerides, sphingolipids in the absence or presence of water].[不同磷脂、甘油单酯、鞘脂在无水或有水情况下液晶相的结构]
J Mol Biol. 1967 May 14;25(3):363-82. doi: 10.1016/0022-2836(67)90192-1.
3
Molecular motion in spin-labeled phospholipids and membranes.自旋标记磷脂和膜中的分子运动。
J Am Chem Soc. 1971 Jan 27;93(2):314-26. doi: 10.1021/ja00731a005.
4
Lamellar and hexagonal lipid phases visualized by freeze-etching.通过冷冻蚀刻观察到的片层状和六方脂质相。
Biochim Biophys Acta. 1970;219(1):47-60. doi: 10.1016/0005-2736(70)90060-x.
5
Bilayer structure in membranes.膜中的双层结构。
Nat New Biol. 1971 Mar 17;230(11):72-6. doi: 10.1038/newbio230072a0.
6
Structure and polymorphism in lipid-water systems, and their possible biological implications.脂质 - 水体系中的结构与多态性及其可能的生物学意义。
Ann N Y Acad Sci. 1966 Jul 14;137(2):409-13. doi: 10.1111/j.1749-6632.1966.tb50172.x.
7
Mixtures of gangliosides and phosphatidylcholine in aqueous dispersions.
Biochim Biophys Acta. 1972 Sep 1;282(1):18-30. doi: 10.1016/0005-2736(72)90307-0.
8
The inter- and intra-molecular mixing of hydrocarbon chains in lecithin-water systems.卵磷脂 - 水体系中烃链的分子间和分子内混合
Chem Phys Lipids. 1972 Mar;8(2):127-33. doi: 10.1016/0009-3084(72)90024-2.
9
The molecular organization of lipids in the membrane of Escherichia coli: phase transitions.大肠杆菌膜中脂质的分子组织：相变
Proc Natl Acad Sci U S A. 1971 Dec;68(12):3180-4. doi: 10.1073/pnas.68.12.3180.
10
Effect of cholesterol and water on the rigidity and order of phosphatidylcholine bilayers.胆固醇和水对磷脂酰胆碱双层膜刚性和有序性的影响。
Biochim Biophys Acta. 1972 Dec 1;290(1):32-42. doi: 10.1016/0005-2736(72)90049-1.
Zotero 插件