Mahoney D F, Wright I G, Goodger B V
Aust Vet J. 1979 Jan;55(1):10-2. doi: 10.1111/j.1751-0813.1979.tb09535.x.
Sixty calves, 3 to 6 months old, were vaccinated once against Babesia bovis in groups of 10, by the following methods: (a) tick infestation; (b) inoculation of virulent parasites obtained from the tick-infested animals immediately after infection; (c) inoculation of the parasites used in (b) attenuated by passage through splenectomised calves; (d) inoculation of commercially-available, living, attenuated vaccine; (e) inoculation of virulent parasites obtained from the tick-infested animals in (a) one year after infection; (f) inoculation of the parasites used in (e) attenuated by passage. All vaccinated animals were maintained tick-free and were strongly immune to challenge with a heterologous strain of B. bovis approximately 4 years after vaccination. There was no difference in immunogenicity between any of the B. bovis populations.
60头3至6月龄的小牛，每组10头，通过以下方法接种了一次抗牛巴贝斯虫疫苗：(a) 蜱虫感染；(b) 接种刚感染后从受蜱虫感染动物身上获取的强毒寄生虫；(c) 接种通过脾切除小牛传代减毒的(b)中所用寄生虫；(d) 接种市售的活减毒疫苗；(e) 接种(a)中受蜱虫感染动物感染一年后获取的强毒寄生虫；(f) 接种通过传代减毒的(e)中所用寄生虫。所有接种疫苗的动物都保持无蜱虫状态，并且在接种疫苗约4年后对异源牛巴贝斯虫菌株的攻击具有很强的免疫力。任何牛巴贝斯虫群体之间的免疫原性没有差异。
