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Antioxidants and carcinogenesis: butylated hydroxytoluene, but not diphenyl-p-phenylenediamine, inhibits cancer induction by N-2-fluorenylacetamide and by N-hydroxy-N-2-fluorenylacetamide in rats.

作者信息

Ulland B M, Weisburger J H, Yamamoto R S, Weisburger E K

出版信息

Food Cosmet Toxicol. 1973 Apr;11(2):199-207. doi: 10.1016/s0015-6264(73)80486-9.

DOI:10.1016/s0015-6264(73)80486-9
PMID:4352030
Abstract
摘要

相似文献

1
Antioxidants and carcinogenesis: butylated hydroxytoluene, but not diphenyl-p-phenylenediamine, inhibits cancer induction by N-2-fluorenylacetamide and by N-hydroxy-N-2-fluorenylacetamide in rats.抗氧化剂与致癌作用：丁基羟基甲苯可抑制大鼠体内由N-2-芴基乙酰胺和N-羟基-N-2-芴基乙酰胺诱导的癌症发生，而二苯胺对苯二胺则无此作用。
Food Cosmet Toxicol. 1973 Apr;11(2):199-207. doi: 10.1016/s0015-6264(73)80486-9.
2
Effect of p-hydroxyacetanilide on liver cancer induction by N hydroxy-N-2-fluorenylacetamide.对羟基乙酰苯胺对N-羟基-N-2-芴基乙酰胺诱导肝癌的影响。
Cancer Res. 1973 Mar;33(3):454-7.
3
Effect of the antioxidant butylated hydroxytoluene (BHT) on the metabolism of the carcinogens N-2-fluorenylacetamide and N-hydroxy-N-2-fluorenylacetamide.抗氧化剂丁基羟基甲苯（BHT）对致癌物N-2-芴基乙酰胺和N-羟基-N-2-芴基乙酰胺代谢的影响。
Food Cosmet Toxicol. 1973 Apr;11(2):209-17. doi: 10.1016/s0015-6264(73)80487-0.
4
The carcinogenicity of fluorenylhydroxamic acids and N-acetoxy-N-fluorenylacetamides for the rat as related to the reactivity of the esters toward nucleophiles.芴基异羟肟酸和N-乙酰氧基-N-芴基乙酰胺对大鼠的致癌性与酯对亲核试剂的反应活性的关系。
Cancer Res. 1975 Feb;35(2):447-59.
5
Effect of acetanilide and p-hydroxyacetanilide on the carcinogenicity of N-2-fluorenylacetamide and N-hydroxy-N-2-fluorenylacetamide in mice, hamsters, and female rats.
J Natl Cancer Inst. 1973 Jul;51(1):235-40. doi: 10.1093/jnci/51.1.235.
6
On the sulfate ester of N-hydroxy-N-2-fluorenylacetamide as a key ultimate hepatocarcinogen in the rat.关于N-羟基-N-2-芴基乙酰胺硫酸酯作为大鼠关键最终致癌物的研究
Cancer Res. 1972 Mar;32(3):491-500.
7
Inhibitory effect of polychlorinated biphenyls on liver tumorigenesis in rats treated with 3'-methyl-4-dimethylaminoazobenzene, n-2-fluorenylacetamide, and diethylnitrosamine.多氯联苯对用3'-甲基-4-二甲基氨基偶氮苯、N-2-芴基乙酰胺和二乙基亚硝胺处理的大鼠肝脏肿瘤发生的抑制作用。
J Natl Cancer Inst. 1974 Nov;53(5):1253-7. doi: 10.1093/jnci/53.5.1253.
8
Simultaneous inhibition of liver carcinogenicity and enhancement of bladder carcinogenicity of N-2-fluorenylacetamide by butylated hydroxytoluene.
Cancer Lett. 1983 May;19(1):55-60. doi: 10.1016/0304-3835(83)90135-0.
9
8-hydroxyquinoline: chronic toxicity and inhibitory effect on the carcinogenicity of N-2-fluorenylacetamide.
Toxicol Appl Pharmacol. 1971 Aug;19(4):687-98. doi: 10.1016/0041-008x(71)90300-0.
10
[Carcinogenic properties of hydrazobenzene].
Vopr Onkol. 1974;20(4):53-7.

引用本文的文献

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The Regulatory Effect of Phytochemicals on Chronic Diseases by Targeting Nrf2-ARE Signaling Pathway.植物化学物通过靶向Nrf2-ARE信号通路对慢性病的调节作用
Antioxidants (Basel). 2023 Jan 20;12(2):236. doi: 10.3390/antiox12020236.
2
NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis.NRF2及其在肿瘤发生起始阶段和后续阶段激活所产生的不确定后果
Cancers (Basel). 2020 Dec 2;12(12):3609. doi: 10.3390/cancers12123609.
3
Effect of antioxidants on the photooxidation of fatty acids.
抗氧化剂对脂肪酸光氧化的影响。
Lipids. 1983 Mar;18(3):259-63. doi: 10.1007/BF02534558.
4
Interaction between dietary selenium and 2-acetylaminofluorene in the rat.膳食硒与 2-乙酰氨基芴在大鼠体内的相互作用。
Biol Trace Elem Res. 1983 Aug;5(4-5):307-15. doi: 10.1007/BF02987216.
5
PET/CT imaging of c-Myc transgenic mice identifies the genotoxic N-nitroso-diethylamine as carcinogen in a short-term cancer bioassay.PET/CT 成像技术在 c-Myc 转基因小鼠中的应用鉴定出了一种遗传毒性的 N-亚硝基二乙胺，其是一种短期癌症生物检测中的致癌物质。
PLoS One. 2012;7(2):e30432. doi: 10.1371/journal.pone.0030432. Epub 2012 Feb 2.
6
Different roles of 8-hydroxyguanine formation and 2-thiobarbituric acid-reacting substance generation in the early phase of liver carcinogenesis induced by a choline-deficient, L-amino acid-defined diet in rats.胆碱缺乏、L-氨基酸限定饮食诱导大鼠肝癌发生早期阶段8-羟基鸟嘌呤形成和2-硫代巴比妥酸反应物质生成的不同作用。
Jpn J Cancer Res. 1994 May;85(5):499-505. doi: 10.1111/j.1349-7006.1994.tb02386.x.
7
Butylated hydroxytoluene: tumor-promoting activity in an in vitro two-stage carcinogenesis assay.丁基羟基甲苯：体外两阶段致癌试验中的促癌活性。
Bull Environ Contam Toxicol. 1982 Jul;29(1):115-20. doi: 10.1007/BF01606098.
8
Modification of the carcinogenic process in colorectal cancer by endogenous and exogenous factors: effect of colestipol hydrochloride on tumors induced by dimethylhydrazine.内源性和外源性因素对结直肠癌致癌过程的修饰：盐酸考来烯胺对二甲基肼诱导肿瘤的影响。
Environ Health Perspect. 1983 Apr;50:91-9. doi: 10.1289/ehp.835091.
9
PBB inhibits metabolic cooperation in Chinese hamster cells in vitro: its potential as a tumor promoter.多溴联苯在体外抑制中国仓鼠细胞的代谢协作：其作为肿瘤促进剂的潜力。
Environ Health Perspect. 1981 Jan;37:179-82. doi: 10.1289/ehp.8137179.
10
Potential inhibitors of colon carcinogenesis.结肠癌发生的潜在抑制剂。
Am J Dig Dis. 1974 Oct;19(10):947-53. doi: 10.1007/BF01076221.