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[Activation of ifosfamide in man and animal].

作者信息

Brock N, Hoefer-Janker H, Hohorst H J, Scheef W, Schneider B, Wolf H C

出版信息

Arzneimittelforschung. 1973 Jan;23(1):1-14.

PMID:4353374
Abstract
摘要

相似文献

1
[Activation of ifosfamide in man and animal].
Arzneimittelforschung. 1973 Jan;23(1):1-14.
2
[Quantitative determination of ifosfamide and an ifosfamide metabolite in the human urine].[人尿中异环磷酰胺及其代谢物的定量测定]
Verh Dtsch Ges Inn Med. 1972;78:1561-4.
3
Isophosphamide as a new acrolein-producing antineoplastic isomer of cyclophosphamide.
Cancer Res. 1972 Nov;32(11):2519-23.
4
Synthesis and metabolic behavior of the suggested active species of isophosphamide having cytostatic activity.
J Med Chem. 1974 Nov;17(11):1237-9. doi: 10.1021/jm00257a024.
5
[Comparison of ifosfamid with cyclophosphamide in the therapy of rat DS carcinosarcoma].异环磷酰胺与环磷酰胺治疗大鼠DS癌肉瘤的比较
Arch Geschwulstforsch. 1971;38(1):15-26.
6
Evidence for an aldehyde possessing alkylating activity as the primary metabolite of cyclophosphamide.有证据表明，一种具有烷基化活性的醛是环磷酰胺的主要代谢产物。
Cancer Res. 1973 Apr;33(4):651-8.
7
[Absorption and organ distribution of the new antidepressant azaphen].新型抗抑郁药阿扎芬的吸收与器官分布
Farmakol Toksikol. 1973 Jul-Aug;26(4):409-11.
8
Metabolism of iphosphamide (2-(2-chloroethylamino)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide) and production of a toxic iphosphamide metabolite.
Cancer Res. 1973 May;33(5):1016-22.
9
Activation of the antineoplastic drug isophosphamide by rat liver microsomes.
J Pharm Pharmacol. 1972 Jul;24(7):585-6. doi: 10.1111/j.2042-7158.1972.tb09065.x.
10
Reactions of 2,2-dimethylaziridine-type alkylating agents in biological systems II: comparative pharmacokinetics in dogs.2,2 - 二甲基氮丙啶类烷基化剂在生物系统中的反应II：犬体内的比较药代动力学
J Pharm Sci. 1975 Feb;64(2):230-5. doi: 10.1002/jps.2600640208.

引用本文的文献

1
Comparison of the genetic activity of cyclophosphamide, ifosfamide and trofosfamide in host-mediated assays with the gene conversion system of yeast.在宿主介导的实验中，使用酵母基因转换系统比较环磷酰胺、异环磷酰胺和曲磷胺的遗传活性。
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1974;81(3-4):261-7. doi: 10.1007/BF00305028.
2
The pharmacokinetics of ifosfamide given as short and long intravenous infusions in cancer patients.癌症患者中短时间和长时间静脉输注异环磷酰胺的药代动力学。
Br J Clin Pharmacol. 1991 Jan;31(1):77-82. doi: 10.1111/j.1365-2125.1991.tb03860.x.
3
Dosing and side-effects of ifosfamide plus mesna.
异环磷酰胺加美司钠的剂量及副作用
J Cancer Res Clin Oncol. 1991;117 Suppl 4(Suppl 4):S164-86. doi: 10.1007/BF01613224.
4
Palliative chemo-radiotherapy with ifosfamide and epirubicin as first-line treatment for high-risk metastatic breast cancer. Results of a prospective multicenter trial.以异环磷酰胺和表柔比星进行姑息性放化疗作为高危转移性乳腺癌的一线治疗。一项前瞻性多中心试验的结果
Cancer Chemother Pharmacol. 1990;26 Suppl:S74-7. doi: 10.1007/BF00685427.
5
Mutagenic activity of cyclophosphamide, ifosfamide, and trofosfamide in different genes of escherichia coli and salmonella typhimurium after biotransformation through extracts of rodent liver.经啮齿动物肝脏提取物生物转化后，环磷酰胺、异环磷酰胺和曲磷胺在大肠杆菌和鼠伤寒沙门氏菌不同基因中的诱变活性。
Arch Toxicol. 1975;33(3):225-40. doi: 10.1007/BF00311275.
6
Excretion patterns of alkylating metabolites in urine following cyclophosphamide treatment of tumor patients: influence of application route, dosage, liver and kidney function.
J Cancer Res Clin Oncol. 1979 Jul 27;94(3):277-86. doi: 10.1007/BF00419287.