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[用超声方法研究囊泡脂质膜]

[Study of vesicular lipid membranes by the ultrasound method].

作者信息

Bukin V A, Sarvazian A P, Pasechnik V I

出版信息

Biofizika. 1979 Jan-Feb;24(1):61-6.

PMID:435544
Abstract

The elastic properties of vesicular lipid membranes using high precision ultrasound velocity measurements in egg lecithin bilayer liposomes suspensions were studied. The temperature and K2SO4 concentration dependence of the hydrophobic part of the membrane elastic properties were obtained. The ionic strength dependence is shown to be linear and to change its sign at 27.5 degrees C. The value of molar volume of egg lecithin molecule hydrophobic part as calculated from acoustical and volumetric data is equal to (665 +/- +/- 63) cm3/mol and its adiabatic compressibility is equal to (58.7 +/- 5.9) . 10(-12) cm2/dyne.

摘要

通过在卵磷脂双层脂质体悬浮液中进行高精度超声速度测量,研究了囊泡脂质膜的弹性特性。得到了膜弹性特性疏水部分的温度和硫酸钾浓度依赖性。结果表明,离子强度依赖性呈线性,且在27.5℃时改变符号。根据声学和体积数据计算得到的卵磷脂分子疏水部分的摩尔体积值为(665±63) cm³/mol,其绝热压缩率为(58.7±5.9)×10⁻¹² cm²/dyne。

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