Andrew C G, Roses A D, Almon R R, Appel S H
Science. 1973 Nov 20;182(4115):927-9. doi: 10.1126/science.182.4115.927.
A membrane-bound protein kinase occurs in membranes derived from rat skeletal muscle and appears limited to a surface membrane fraction. The enzyme is magnesium dependent, is only minimally stimulated by cyclic nucleotides, and phosphorylates serine and to a lesser extent threonine residues of three membrane proteins with molecular weights of less than 30,000.
一种膜结合蛋白激酶存在于源自大鼠骨骼肌的膜中,且似乎局限于表面膜部分。该酶依赖镁,仅受到环核苷酸的微弱刺激,并使三种分子量小于30,000的膜蛋白的丝氨酸残基磷酸化,对苏氨酸残基的磷酸化程度较低。