Sokolov Iu V, Lishko U K
Biokhimiia. 1979 Feb;44(2):317-23.
Lecithine-cholesterol liposomes containing amphotericin B ionoforic marker were used to study the interaction between liposomes and planar phospholipid membranes. The liposomes were shown to increase the permeability of the planar membrane, which may be explained in terms of membrane fusion. Bivalent cations (Mg2+ and particularly Ca2+), dicetylphosphate producing negatively charged groups on the membrane surface and the n-decane suspension in water promote the fusion, whereas the increase of the cholesterol content in the liposomes prevents it.
含有两性霉素B离子载体标记物的卵磷脂-胆固醇脂质体被用于研究脂质体与平面磷脂膜之间的相互作用。结果表明，脂质体可增加平面膜的通透性，这可以用膜融合来解释。二价阳离子（Mg2+，尤其是Ca2+）、在膜表面产生带负电荷基团的十六烷基磷酸酯以及正癸烷水悬浮液可促进融合，而脂质体中胆固醇含量的增加则会抑制融合。
