甲型肝炎：通过免疫电子显微镜检测与急性疾病相关的病毒样抗原。
Hepatitis A: detection by immune electron microscopy of a viruslike antigen associated with acute illness.
作者信息
Feinstone S M, Kapikian A Z, Purceli R H
出版信息
Science. 1973 Dec 7;182(4116):1026-8. doi: 10.1126/science.182.4116.1026.
PMID:4356028
Abstract
Spherical 27-nanometer particles were visualized in stools obtained from hepatitis A patients in the acute phase of the disease. The particle was serologically specific for this disease, and every hepatitis A patient tested demonstrated a serologic response to this antigen. The findings suggest that it is the etiologic agent of hepatitis A.
摘要
在甲型肝炎急性期患者的粪便中发现了直径为27纳米的球形颗粒。这种颗粒对此病具有血清学特异性，且每例接受检测的甲型肝炎患者均对此抗原呈现血清学反应。这些发现提示该颗粒是甲型肝炎的病原体。
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