Pavlov H, Goldman A B, Arnold W D
Br J Radiol. 1979 Mar;52(615):173-80. doi: 10.1259/0007-1285-52-615-173.
Radiographs of the hands and feet of 72 haemophilic patients were reviewed for peripheral joint involvement. Fifty patients or 69% had changes in the small joints of their hands and/or feet with a total of 160 abnormal joints. In the hands the metacarpo-phalangeal joints were predominantly involved (42 of 50 joints), and in the feet, the metatarso-phalangeal joints (68 of 110 abnormal joints), as well as the posterior subtalar joint (36 of 110 joints). Röntgen abnormalities were characterized by irregularity and/or flattening of the articular cortices. The involvement of the small peripheral joint in haemophilic patients has not been a primary consideration in previous clinical and radiographic studies because of the more common and more debilitating changes in the large joints. The recognition of involvement of the small joints is described to avoid misinterpretation of the röntgen findings and to appreciate the incidence of involvement, especially with the increased availability of replacement therapy.
对72例血友病患者的手足X线片进行回顾，以评估外周关节受累情况。50例患者（占69%）的手部和/或足部小关节出现改变，共有160个异常关节。手部以掌指关节受累为主（50个关节中有42个），足部以跖趾关节（110个异常关节中有68个）以及距下后关节（110个关节中有36个）受累为主。X线异常表现为关节皮质不规则和/或变平。由于大关节中更常见且更使人衰弱的改变，血友病患者外周小关节受累在以往的临床和影像学研究中未被作为主要考虑因素。描述小关节受累情况是为了避免对X线检查结果的误解，并了解受累发生率，尤其是在替代治疗可及性增加的情况下。
