Lambert M E, Schofield P F, Ironside A G, Mandal B K
Br Med J. 1979 Mar 31;1(6167):857-9. doi: 10.1136/bmj.1.6167.857.
Eleven consecutive patients with diarrhoea from whose stools campylobacter were isolated were investigated by sigmoidoscopy and rectal biopsy. Eight had definite proctitis, and in seven biopsy specimens were abnormal with histological changes ranging from non-specific colitis to gross colitis with goblet-cell depletion and crypt-abscess formation. Nine of the patients passed blood in their stools, and in all but one abdominal pain was a feature of the illness. Severe campylobacter colitis may be clinically, sigmoidoscopically, and histologically difficult to differentiate from ulcerative colitis and is a differential diagnosis in acute colitis.
对11例连续腹泻且粪便中分离出弯曲杆菌的患者进行了乙状结肠镜检查和直肠活检。8例有明确的直肠炎，7例活检标本异常，组织学改变从非特异性结肠炎到伴有杯状细胞减少和隐窝脓肿形成的严重结肠炎不等。9例患者粪便带血，除1例之外所有患者均有腹痛症状。严重的弯曲杆菌性结肠炎在临床、乙状结肠镜检查和组织学上可能难以与溃疡性结肠炎区分，是急性结肠炎中的一个鉴别诊断。
