Wentworth P, Jentz L A, Croal A E
Can Med Assoc J. 1979 Mar 17;120(6):676-80, 706.
The records of all 2427 autopsies performed at the Brantford (Ont.) General and Paris (Ont.) Willett hospitals from Jan. 1, 1969 to Aug. 15, 1978 were reviewed. Of the 1299 cases of sudden unexpected death investigated by a coroner almost 28% were due to unnatural causes--violence or poisoning. The main cause of natural sudden death was coronary artery disease, which accounted for 43.3% of all the sudden unexpected deaths. In 20 cases the cause of death was thought to be viral myocarditis, and in 9 of the 20 there was serologic evidence of at least previous coxsackievirus disease. Two of the nine cases were of special interest because of the finding of giant-cell myocarditis in one and aortic valve disease in the other. Eleven of the 20 persons were aged 13 to 46 years. These findings support the view that the most serious manifestation of enterovirus infection today is cardiac damage by coxsackieviruses.
对1969年1月1日至1978年8月15日在安大略省布兰特福德综合医院和安大略省巴黎威利特医院进行的2427例尸检记录进行了回顾。在验尸官调查的1299例意外猝死病例中，近28%是由非自然原因——暴力或中毒导致的。自然猝死的主要原因是冠状动脉疾病，占所有意外猝死病例的43.3%。有20例死亡原因被认为是病毒性心肌炎，在这20例中有9例至少有先前柯萨奇病毒病的血清学证据。这9例中有2例特别值得关注，因为其中1例发现了巨细胞心肌炎，另1例发现了主动脉瓣疾病。这20人中有11人的年龄在13至46岁之间。这些发现支持了这样一种观点，即如今肠道病毒感染最严重的表现是柯萨奇病毒对心脏的损害。
