人绒毛膜促性腺激素的放射受体测定：早期妊娠的检测
Radioreceptor assay of human chorionic gonadotropin: detection of early pregnancy.
作者信息
Saxena B B, Hasan S H, Haour F, Schmidt-Gollwitzer M
出版信息
Science. 1974 May 17;184(4138):793-5. doi: 10.1126/science.184.4138.793.
PMID:4362476
Abstract
A rapid, sensitive, and specific radioreceptor assay for the determination of human chorionic gonadotropin and luteinizing hormone in plasma is described. Plasma membranes of bovine corpora lutea of early pregnancy, which bind biologically active labeled human chorionic gonadotropin, have been used as receptor. Pregnancy could be detected by assaying the gonadotropin in plasma samples obtained from day 6 to 8 after conception.
摘要
本文描述了一种用于测定血浆中人绒毛膜促性腺激素和促黄体生成素的快速、灵敏且特异的放射受体测定法。妊娠早期牛黄体的质膜可结合具有生物活性的标记人绒毛膜促性腺激素，已被用作受体。通过检测受孕后第6至8天采集的血浆样本中的促性腺激素，可检测出妊娠情况。
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