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人绒毛膜促性腺激素的放射受体测定:早期妊娠的检测

Radioreceptor assay of human chorionic gonadotropin: detection of early pregnancy.

作者信息

Saxena B B, Hasan S H, Haour F, Schmidt-Gollwitzer M

出版信息

Science. 1974 May 17;184(4138):793-5. doi: 10.1126/science.184.4138.793.

DOI:10.1126/science.184.4138.793
PMID:4362476
Abstract

A rapid, sensitive, and specific radioreceptor assay for the determination of human chorionic gonadotropin and luteinizing hormone in plasma is described. Plasma membranes of bovine corpora lutea of early pregnancy, which bind biologically active labeled human chorionic gonadotropin, have been used as receptor. Pregnancy could be detected by assaying the gonadotropin in plasma samples obtained from day 6 to 8 after conception.

摘要

本文描述了一种用于测定血浆中人绒毛膜促性腺激素和促黄体生成素的快速、灵敏且特异的放射受体测定法。妊娠早期牛黄体的质膜可结合具有生物活性的标记人绒毛膜促性腺激素,已被用作受体。通过检测受孕后第6至8天采集的血浆样本中的促性腺激素,可检测出妊娠情况。

相似文献

1
Radioreceptor assay of human chorionic gonadotropin: detection of early pregnancy.人绒毛膜促性腺激素的放射受体测定:早期妊娠的检测
Science. 1974 May 17;184(4138):793-5. doi: 10.1126/science.184.4138.793.
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The use of a radioreceptorassay of human chorionic gonadotropin for the diagnosis and management of ectopic pregnancy.
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Isolation of the luteinizing hormone-chorionic gonadotropin receptor in high yield from bovine corpora lutea. Molecular assembly and oligomeric nature.从牛黄体中高产率分离促黄体生成素 - 绒毛膜促性腺激素受体。分子组装和寡聚性质。
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引用本文的文献

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From Cereal Grains to Immunochemistry-What Role Have Antibodies Played in the History of the Home Pregnancy Test.从谷物到免疫化学——抗体在家庭妊娠试验历史中扮演了什么角色。
Antibodies (Basel). 2023 Aug 31;12(3):56. doi: 10.3390/antib12030056.
2
Choriogonadotropin-like antigen in a strain of Streptococcus faecalis and a strain of Staphylococcus simulans: detection, identification, and characterization.粪肠球菌菌株和模仿葡萄球菌菌株中的绒毛膜促性腺激素样抗原:检测、鉴定与特性分析
Infect Immun. 1981 Jan;31(1):487-94. doi: 10.1128/iai.31.1.487-494.1981.
3
Detection of pregnancy specific protein SP-1 by enzyme immunoassay in early pregnancy.
酶免疫测定法检测早期妊娠时的妊娠特异性蛋白SP-1
Arch Gynecol. 1983;233(3):149-53. doi: 10.1007/BF02114595.
4
Current trends in antifertility vaccine research.抗生育疫苗研究的当前趋势。
West J Med. 1985 Feb;142(2):197-202.
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Biological markers during early pregnancy: trophoblastic signals of the peri-implantation period.早孕期的生物标志物:着床期的滋养层信号
Environ Health Perspect. 1987 Oct;74:129-47. doi: 10.1289/ehp.8774129.
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Isoimmunization against human chorionic gonadotropin with conjugates of processed beta-subunit of the hormone and tetanus toxoid.用激素的加工β亚基与破伤风类毒素的结合物进行人绒毛膜促性腺激素的同种免疫。
Proc Natl Acad Sci U S A. 1976 Jan;73(1):218-22. doi: 10.1073/pnas.73.1.218.
7
The effect of prostaglandin f2alpha on endocrine parameters in early pregnancy.前列腺素F2α对妊娠早期内分泌参数的影响。
Arch Gynakol. 1977 Mar 31;222(2):149-57. doi: 10.1007/BF00667198.
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Production of choriogonadotropin-like factor by a microorganism.微生物产生类绒毛膜促性腺激素因子。
Proc Natl Acad Sci U S A. 1979 Dec;76(12):6622-6. doi: 10.1073/pnas.76.12.6622.
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The impact of peptide hormone receptor research on clinical medicine.肽类激素受体研究对临床医学的影响。
J R Coll Physicians Lond. 1978 Jul;12(4):379-97.