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甲状旁腺癌:通过甲状旁腺激素测定确定盆腔转移灶的位置。

Parathyroid carcinoma: location of pelvic metastases by parathyroid hormone assay.

作者信息

Murray T M, Patt N L, Muzaffar S A

出版信息

Can Med Assoc J. 1974 Apr 6;110(7):809-10 passim.

Abstract

A metastasis from a functioning parathyroid carcinoma was located by PTH radioimmunoassay and selective venous catheterization. The site of the metastasis, verified at autopsy, was in the right side of the pelvis. This is the most distant reported location for metastatic parathyroid carcinoma. The patient's plasma immunoreactive PTH rose more than twofold in response to induced hypocalcemia. This suggests that relative hypocalcemia, induced therapeutically in such patients, may result in a higher chronic level of PTH secretion.

摘要

通过甲状旁腺激素放射免疫测定和选择性静脉插管定位了一例功能性甲状旁腺癌的转移灶。尸检证实转移部位在骨盆右侧。这是报道的甲状旁腺癌转移最远处的位置。患者的血浆免疫反应性甲状旁腺激素在诱导性低钙血症反应中升高了两倍多。这表明在此类患者中通过治疗诱导的相对低钙血症可能导致更高的慢性甲状旁腺激素分泌水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26e5/1947441/021ff4b14578/canmedaj01579-0072-a.jpg

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IMMUNOASSAY OF BOVINE AND HUMAN PARATHYROID HORMONE.牛和人甲状旁腺激素的免疫测定
Proc Natl Acad Sci U S A. 1963 May;49(5):613-7. doi: 10.1073/pnas.49.5.613.
7
Hyperparathyroidism. Clinical experiences from 208 cases.
Ups J Med Sci. 1972;77(1):41-6. doi: 10.1517/03009734000000008.
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Parathyroid carcinoma: a collective review.甲状旁腺癌:一项综合综述。
Ann Surg. 1969 Apr;169(4):631-40. doi: 10.1097/00000658-196904000-00022.

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