Dzhirkolova T, Dishovski Kh, Rusev G
Eksp Med Morfol. 1979;18(1):31-5.
The authors found that the contractile activity of isolated myofibers as-well as superprecipitation of myosin B were reduced after intoxication of white rats with 1/2 of dose of LD50 of neguvon. The reaktivator of cholinesterase TMB-4 (20 mg/kg) recovered the contractile capability of myofibres even on the third day after treatment, but superprecipitation of myosin B-after the twentieth day.
作者发现,用1/2半数致死剂量的内吸磷对大白鼠进行中毒处理后,离体肌纤维的收缩活性以及肌球蛋白B的超沉淀作用均降低。胆碱酯酶复活剂TMB - 4(20毫克/千克)即使在处理后的第三天也能恢复肌纤维的收缩能力,但肌球蛋白B的超沉淀作用在第二十天后才恢复。