Chowdhury M, Steinberger E
Fertil Steril. 1979 Mar;31(3):328-30. doi: 10.1016/s0015-0282(16)43883-5.
Levels of human chorionic gonadotropin (HCG) were determined in testicular tissue of young, apparently normal men; older men with carcinoma of the prostate; male transsexuals treated with estrogens; and also in seminal plasma of normal and vasectomized patients. In all samples with one exception (a 76-year-old male with cancer of the prostate), immunoreactive HCG activity could be detected. The immunoassayable HCG content was higher in testicular extracts from young adults as compared with older men with cancer of the prostate. In transsexuals receiving estrogen therapy, testicular HCG levels were also very low. A possible relationship between quantitatively normal spermatogenesis and the testicular HCG level has been discussed. HCG was detected in seminal plasma from both normal and vasectomized men. The origin of this HCG activity may be extratesticular, and the possible role of the prostate and seminal vesicle in the production of HCG-like activity has to be considered.
在看似正常的年轻男性、患有前列腺癌的老年男性、接受雌激素治疗的男性易性癖者的睾丸组织中，以及正常和输精管切除患者的精浆中，测定了人绒毛膜促性腺激素（HCG）的水平。除了一个例外样本（一名76岁患有前列腺癌的男性），在所有样本中均检测到了免疫反应性HCG活性。与患有前列腺癌的老年男性相比，年轻成年人睾丸提取物中的可免疫测定的HCG含量更高。在接受雌激素治疗的易性癖者中，睾丸HCG水平也非常低。已经讨论了定量正常的精子发生与睾丸HCG水平之间的可能关系。在正常男性和输精管切除男性的精浆中均检测到了HCG。这种HCG活性的来源可能在睾丸外，必须考虑前列腺和精囊在产生类似HCG活性中的可能作用。
