Carstens H B, Schrodt G R
Am J Pathol. 1974 Dec;77(3):377-86.
Specimens from 9 patients with the varying histopathologic patterns of sclerosing hemangioma were studied by electron microscopy. Not only were there numerous identifiable vascular spaces, but many of the cells had the ultrastructural characteristics of endothelial cells whether they were lining vascular spaces, forming organoid structures or were isolated. The Weibel-Palade bodies served as a marker for endothelial cells. They are rod-shaped, with a length up to 2 mu and a diameter up to .1 mu, and contain a tubular substructure, the diameter of the individual tubules being 150 [unk]. Our findings clearly support Gross and Wolbach's theory that this group of lesions is of endothelial origin.
对9例具有不同组织病理学模式的硬化性血管瘤患者的标本进行了电子显微镜研究。不仅有大量可识别的血管腔隙,而且许多细胞无论其是衬于血管腔隙内、形成类器官结构还是孤立存在,都具有内皮细胞的超微结构特征。魏贝尔-帕拉德小体作为内皮细胞的标志物。它们呈杆状,长度可达2微米,直径可达0.1微米,并含有管状亚结构,单个小管的直径为150埃。我们的研究结果明确支持格罗斯和沃尔巴赫的理论,即这一组病变起源于内皮细胞。