海兔单个已鉴定神经元中几种假定神经递质的共存。
Coexistence of several putative neurotransmitters in single identified neurons of Aplysia.
作者信息
Brownstein M J, Saavedra J M, Axelrod J, Zeman G H, Carpenter D O
出版信息
Proc Natl Acad Sci U S A. 1974 Dec;71(12):4662-5. doi: 10.1073/pnas.71.12.4662.
Abstract
By sensitive enzymatic micromethods several putative neurotransmitters were measured in four identifiable neurons of Aplysia californica (R-2, R-14, L-11, and C-1). Serotonin was found in all of these neurons, and octopamine in all but C-1. Acetylcholine has been previously reported to be present in R-2 and L-11. The catecholamines, norepinephrine and dopamine, were not detected in the four cells examined. The possible biological consequence of the presence of several putative transmitters in single identifiable neurons is discussed.
摘要
通过灵敏的酶促微量法，在加州海兔的四个可识别神经元（R-2、R-14、L-11和C-1）中检测了几种假定的神经递质。在所有这些神经元中都发现了5-羟色胺，除C-1外的所有神经元中都发现了章鱼胺。先前已有报道称乙酰胆碱存在于R-2和L-11中。在所检测的四个细胞中未检测到儿茶酚胺、去甲肾上腺素和多巴胺。本文讨论了单个可识别神经元中存在几种假定递质的可能生物学后果。
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