Krainick J U, Thoden U
J Neurosurg Sci. 1974 Jul-Sep;18(3):187-9.
The results of DCS in 50 patients are altogether favourable; they are better for the group of amputation and phantom pain than for the group of peripheral nerve lesions. For patients with malignoma pain no valid comment can be given. The influence of DCS is mostly immediate in bouts of acute pain, slower in chronic permanent pain, where a longer period of stimulation is needed. The observation of such longer stimulation periods together with the experience that during DCS there is a shift in the pain threshold, even in segments above the stimulus including also the face, seems to indicate a participation of higher neuronal centers in the assumed gate control.
50例患者接受深部脑刺激（DCS）的结果总体良好；对于截肢和幻肢痛组，其效果优于周围神经损伤组。对于恶性肿瘤疼痛患者，无法给出有效的评价。DCS对急性疼痛发作的影响大多是即时的，对慢性持续性疼痛的影响则较慢，后者需要更长时间的刺激。观察到如此长的刺激期，再加上在DCS期间疼痛阈值会发生变化的经验，即使在刺激部位以上的节段（包括面部）也是如此，这似乎表明在假定的闸门控制中，高级神经中枢参与其中。
