小鼠长期吸入新鲜香烟烟雾后移植瘤的生长情况。
The growth of transplanted tumours in mice after chronic inhalation of fresh cigarette smoke.
作者信息
Thomas W R, Holt P G, Papadimitriou J M, Keast D
出版信息
Br J Cancer. 1974 Nov;30(5):459-62. doi: 10.1038/bjc.1974.220.
Abstract
The subcutaneous growth of the Lewis lung tumour in C57BL mice chronically exposed to fresh cigarette smoke was increased above that in age-matched control mice. When murine sarcoma virus (Harvey) induced tumour cells were introduced to the lungs of groups of BALB/c mice, only mice chronically exposed to fresh cigarette smoke died with tumour cells in the lungs. Tumour cell growth in mice during short term cigarette smoke exposure was indistinguishable from that in controls.
摘要
长期暴露于新鲜香烟烟雾中的C57BL小鼠体内，Lewis肺癌的皮下生长比年龄匹配的对照小鼠有所增加。当将鼠肉瘤病毒（哈维）诱导的肿瘤细胞引入BALB/c小鼠组的肺部时，只有长期暴露于新鲜香烟烟雾中的小鼠肺部出现肿瘤细胞并死亡。短期香烟烟雾暴露期间小鼠体内肿瘤细胞的生长与对照组无明显差异。
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