Eisenberg W V
Environ Health Perspect. 1974 Dec;9:183-91. doi: 10.1289/ehp.749183.
Inorganic particulate matter in foods and drugs is discussed from the standpoint of determination by optical microscopy, source, and regulatory significance. Some particulate matter may be generated as extraneous material and traced to specific operational practices during processing and production with excessive levels associated with deficiencies in good manufacturing practices. Other particles, such as talc and asbestos, may be incorporated as additives during their use in production. Data on particles in parenteral drugs are discussed generally. Specific data on glass particles in foods and sand and soil particles in spices are presented.
从光学显微镜测定、来源及监管意义的角度,对食品和药品中的无机颗粒物进行了讨论。一些颗粒物可能作为外来物质产生,并可追溯到加工和生产过程中的特定操作规范,过量水平与良好生产规范的缺陷相关。其他颗粒,如滑石粉和石棉,可能在生产使用过程中作为添加剂混入。文中对注射用药品中的颗粒数据进行了总体讨论。还给出了食品中玻璃颗粒以及香料中沙粒和土壤颗粒的具体数据。