Okudaira Y, Strauss L
Obstet Gynecol. 1967 Aug;30(2):172-87.
The ultrastructure of molar trophoblast is described in hydatidiform mole and chorioadenoma destruens. Villous molar trophoblast exhibits only minor deviations from normal early villous trophoblast. Invasive trophoblast of chorioadenoma destruens shows features of more-active cell growth, multiplication, differentiation, and degradation. Evidence for evolution of highly differentiated syncytial trophoblast via intermediate stages from primitive undifferentiated cytotrophoblast is confirmed. Cytoplasmic inclusions resembling virus-like particles, observed in chorioadenoma destruens, have not been hitherto described in normal or pathologic trophoblast.
本文描述了葡萄胎和侵袭性葡萄胎中磨牙滋养层的超微结构。绒毛状葡萄胎滋养层与正常早期绒毛滋养层相比仅有轻微差异。侵袭性葡萄胎的侵袭性滋养层表现出细胞生长、增殖、分化和降解更活跃的特征。证实了高分化合体滋养层从原始未分化细胞滋养层经中间阶段演变而来的证据。在侵袭性葡萄胎中观察到的类似病毒样颗粒的细胞质内含物，迄今在正常或病理滋养层中尚未见报道。
