肺癌患者中芳烃羟化酶诱导性与成淋巴细胞形成

Aryl hydrocarbon hydroxylase inducibility and lymphoblast formation in lung cancer patients.

作者信息

Prasad R, Prasad N, Harrell J E, Thornby J, Liem J H, Hudgins P T, Tsuang J

出版信息

Int J Cancer. 1979 Mar 15;23(3):316-20. doi: 10.1002/ijc.2910230308.

Abstract

Aryl hydrocarbon hydroxylase (AHH) inducibility and lymphoblast formation were studied in lymphocytes from healthy control subjects and from lung cancer patients undergoing radiotherapy. The relationship between AHH inducibility and percentage lymphoblasts was statistically significant only for the pre-treatment patients (r = 0.598; p less than 0.05). In the control group and in patients undergoing radiotherapy the correlation between AHH inducibility and lymphoblast formation was positive but statistically it was not significant. Our data do not suggest a linear relationship between AHH inducibility and lymphoblast formation.

摘要

对健康对照者以及接受放疗的肺癌患者的淋巴细胞进行了芳烃羟化酶（AHH）诱导性和淋巴母细胞形成的研究。仅在治疗前的患者中，AHH诱导性与淋巴母细胞百分比之间的关系具有统计学意义（r = 0.598；p小于0.05）。在对照组和接受放疗的患者中，AHH诱导性与淋巴母细胞形成之间的相关性为正，但在统计学上不显著。我们的数据并未表明AHH诱导性与淋巴母细胞形成之间存在线性关系。