匹莫林：增强脑内RNA聚合酶活性。

Magnesium pemoline: enhancement of brain RNA polymerases.

作者信息

Glasky A J, Simon L N

出版信息

Science. 1966 Feb 11;151(3711):702-3. doi: 10.1126/science.151.3711.702.

DOI:10.1126/science.151.3711.702

Abstract

The stimulation by magnesium pemoline of systems that synthesize brain nucleic acid was studied in vivo and in vitro. There are differential effects between true RNA polymerase and pseudo-RNA polymerase. The selective stimulation of true RNA polymerase by magnesium pemoline was not observed with stimulants of the central nervous system and psychotropic agents.

摘要

在体内和体外研究了匹莫林对合成脑核酸系统的刺激作用。真核RNA聚合酶和假RNA聚合酶之间存在差异效应。中枢神经系统兴奋剂和精神药物未观察到匹莫林对真核RNA聚合酶的选择性刺激作用。