Frey P W, Polidora V J
Science. 1967 Mar 10;155(3767):1281-2. doi: 10.1126/science.155.3767.1281.
Rats administered 20 milligrams of magnesium pemoline per kilo gram of body weight learned to avoid shock in a jump-out apparatus in fewer trials than did controls. However, the results suggested that the principal effect of the drug was to facilitate the avoidance behavior of those animals that tended to "freeze" in response to electric grid shock. No differences in retention were observed between experimental and control animals that had achieved equal levels of learnine.
给每公斤体重注射20毫克匹莫林的大鼠，在跳台装置中学会避免电击所需的试验次数比对照组少。然而，结果表明该药物的主要作用是促进那些在电网电击时倾向于“僵住”的动物的回避行为。在学习水平相同的实验动物和对照动物之间，未观察到记忆保持方面的差异。
