所选青霉素在体外及小鼠实验性细菌感染中的活性。
Activity of selected penicillins in vitro and in experimental bacterial infections in mice.
作者信息
Miraglia G J, Basch H I
出版信息
Appl Microbiol. 1967 May;15(3):566-8. doi: 10.1128/am.15.3.566-568.1967.
Abstract
The minimal inhibitory concentration and the 50% mouse protective dose for five key penicillins are presented. Such data provide a useful guide in evaluating the activity of new penicillins, in comparison with those already commercially available, and establishes the amounts of antibiotic necessary to obtain a PD(50) for several experimental model infections in mice.
摘要
文中给出了五种关键青霉素的最低抑菌浓度和50%小鼠保护剂量。这些数据为评估新型青霉素的活性提供了有用的指导，可与已上市的青霉素进行比较，并确定在小鼠的几种实验模型感染中获得50%保护剂量（PD50）所需的抗生素量。
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