The absorption and urinary excretion in man of fenfluramine and its main metabolite.

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作者信息

Beckett A H, Brookes L G

出版信息

J Pharm Pharmacol. 1967 Dec;19:Suppl:42S-49S.

PMID:4383855

Abstract

摘要

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The absorption and urinary excretion in man of fenfluramine and its main metabolite.

J Pharm Pharmacol. 1967 Dec;19:Suppl:42S-49S.

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引用本文的文献

In vitro evaluation suggests fenfluramine and norfenfluramine are unlikely to act as perpetrators of drug interactions.体外评估表明，芬氟拉明和 norfenfluramine 不太可能作为药物相互作用的罪魁祸首。

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In vitro evaluation of fenfluramine and norfenfluramine as victims of drug interactions.氟苯丙胺和去甲氟苯丙胺作为药物相互作用的牺牲品的体外评估。

Pharmacol Res Perspect. 2022 Jun;10(3):e00958. doi: 10.1002/prp2.958.

A phase I, randomized, open-label, single-dose, 3-period crossover study to evaluate the drug-drug interaction between ZX008 (fenfluramine HCl oral solution) and a regimen of stiripentol, clobazam, and valproate in healthy subjects .一项I期随机、开放标签、单剂量、3期交叉研究，旨在评估健康受试者中ZX008（盐酸芬氟拉明口服溶液）与司替戊醇、氯巴占和丙戊酸盐联合用药之间的药物相互作用。

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Pharmacokinetics of fenfluramine and norfenfluramine in volunteers given D- and DL-fenfluramine for 15 days.给予D-和DL-芬氟拉明15天的志愿者体内芬氟拉明和去甲芬氟拉明的药代动力学

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Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure.药理活性药物代谢物：治疗及毒性活性、人体血浆及尿液数据、肾衰竭时的蓄积情况

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