Isenberg H D
Appl Microbiol. 1967 Sep;15(5):1074-8. doi: 10.1128/am.15.5.1074-1078.1967.
Doxycycline (alpha-6-deoxy-oxytetracycline) was tested against various bacteria of recent clinical origin with 30-mug discs. The antibiotic susceptibility of these bacteria to commonly used antimicrobial agents was also established. Those bacteria which responded with equivocal zones of inhibition about the tetracycline compounds were tested by the tube dilution technique. Staphylococci and enterococci consistently displayed greater in vitro susceptibility to doxycycline than to tetracycline or demethylchlortetracycline.
用含30微克强力霉素(α-6-脱氧土霉素)的药敏纸片对近期临床分离的多种细菌进行了测试。同时也确定了这些细菌对常用抗菌药物的敏感性。对四环素类化合物抑菌圈不明确的细菌,采用试管稀释法进行测试。葡萄球菌和肠球菌在体外对强力霉素的敏感性始终高于四环素或去甲金霉素。