• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Enzymic studies of bile acid metabolism. I. 6-beta-Hydroxylation of chenodeoxycholic and taurochenodeoxycholic acids by microsomal preparations of rat liver.

作者信息

Voigt W, Thomas P J, Hsia S L

出版信息

J Biol Chem. 1968 Jun 25;243(12):3493-9.

PMID:4385344
Abstract
摘要

相似文献

1
Enzymic studies of bile acid metabolism. I. 6-beta-Hydroxylation of chenodeoxycholic and taurochenodeoxycholic acids by microsomal preparations of rat liver.胆汁酸代谢的酶学研究。I. 大鼠肝脏微粒体制剂对鹅去氧胆酸和牛磺鹅去氧胆酸的6-β-羟基化作用
J Biol Chem. 1968 Jun 25;243(12):3493-9.
2
7 -Hydroxylation of taurodeoxycholic acid by a reconstituted system from rat liver microsomes.
Biochem Biophys Res Commun. 1973 Jul 17;53(2):609-16. doi: 10.1016/0006-291x(73)90705-5.
3
A fatty acid gamma-hydroxylation system solubilized from porcine kidney cortex microsomes.从猪肾皮质微粒体中溶解出的脂肪酸γ-羟基化系统。
Biochim Biophys Acta. 1971 Jul 13;239(2):178-89.
4
Cytochrome P 450K of rat kidney cortex microsomes: its involvement in fatty acid - and ( -1)-hydroxylation.大鼠肾皮质微粒体的细胞色素P 450K：其在脂肪酸和（-1）-羟基化中的作用。
Arch Biochem Biophys. 1972 May;150(1):64-71. doi: 10.1016/0003-9861(72)90010-0.
5
Metabolism of steroid hormones, sterols, and bile acids in liver microsomes from male, female, and male-pseudohermaphroditic rats.雄性、雌性及雄性假两性畸形大鼠肝脏微粒体中甾体激素、甾醇和胆汁酸的代谢
Eur J Biochem. 1972 Dec 4;31(2):345-53. doi: 10.1111/j.1432-1033.1972.tb02539.x.
6
Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components.将肝微粒体中含细胞色素P - 450的ω-羟化系统解析为三个组分。
J Biol Chem. 1969 Jul 10;244(13):3714-21.
7
[New method for the separation and determination of cholhydroxamic acid. Application to the study of cholyl-coenzyme A formation during the condensation of cholic acid and taurine catalyzed by rat liver microsomes].[胆异羟肟酸的分离与测定新方法。应用于大鼠肝微粒体催化胆酸与牛磺酸缩合过程中胆酰辅酶A形成的研究]
Bull Soc Chim Biol (Paris). 1967 Nov 10;49(10):1369-87.
8
Inhibitory effect of carbon monoxide on the hydroxylation of testosterone by rat liver microsomes.一氧化碳对大鼠肝脏微粒体睾酮羟化作用的抑制效应。
J Biol Chem. 1968 Jul 25;243(14):3912-5.
9
The effect of 3-sulphation and taurine conjugation on the uptake of chenodeoxycholic acid by rat hepatocytes.3-硫酸化和牛磺酸共轭对大鼠肝细胞摄取鹅去氧胆酸的影响。
Biochim Biophys Acta. 1983 Nov 1;754(1):101-9. doi: 10.1016/0005-2760(83)90086-3.
10
Effect of biliary obstruction on formation and metabolism of bile acids in rat.
Steroids. 1973 Oct;22(4):567-79. doi: 10.1016/0039-128x(73)90013-5.

引用本文的文献

1
Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph-Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavailability in Mice.代谢弱点与药代动力学：以胆汁酸为核心的Eph-Ephrin拮抗剂C-3位官能化作为在小鼠中获得口服生物利用度的有效策略
Pharmaceuticals (Basel). 2021 Dec 28;15(1):41. doi: 10.3390/ph15010041.
2
Targeted Analysis of 46 Bile Acids to Study the Effect of Acetaminophen in Rat by LC-MS/MS.通过液相色谱-串联质谱法对46种胆汁酸进行靶向分析以研究对乙酰氨基酚在大鼠体内的作用
Metabolites. 2020 Jan 7;10(1):26. doi: 10.3390/metabo10010026.
3
Engineered three-dimensional liver mimics recapitulate critical rat-specific bile acid pathways.
工程化三维肝脏模拟物再现关键的大鼠特异性胆汁酸途径。
Tissue Eng Part A. 2011 Mar;17(5-6):677-89. doi: 10.1089/ten.TEA.2010.0423. Epub 2010 Dec 19.
4
[Atypical bile acids (author's transl)].[非典型胆汁酸（作者译）]
Klin Wochenschr. 1980 Jan 15;58(2):55-63. doi: 10.1007/BF01477189.
5
Effect of bile acid feeding on hepatic steroid 12 alpha-hydroxylase activity in hamsters.胆汁酸喂养对仓鼠肝脏类固醇12α-羟化酶活性的影响。
Lipids. 1983 Nov;18(11):789-94. doi: 10.1007/BF02534637.
6
Bile acid composition of rainbow trout, Salmo gairdneri.虹鳟（Salmo gairdneri）的胆汁酸组成
Lipids. 1974 Dec;9(12):945-51. doi: 10.1007/BF02533816.
7
Distinct forms of cytochrome P-450 are responsible for 6 beta-hydroxylation of bile acids and of neutral steroids.细胞色素P-450的不同形式负责胆汁酸和中性类固醇的6β-羟基化。
Biochem J. 1991 Apr 1;275 ( Pt 1)(Pt 1):105-11. doi: 10.1042/bj2750105.