Gosden C, Ross A, McGovern A, Reid W
J Reprod Fertil. 1979 Mar;55(2):437-46. doi: 10.1530/jrf.0.0550437.
Of the 8 pregnancies studied, 2 were of small gestational sacs with blighted ova and were associated with devices in which the copper wire had very high detectable X-ray emissions for copper (greater than 90%). In 2 other pregnancies intrauterine deaths had occurred by the time of termination at 13 and 17 weeks and copper levels in the products of conception were variable. There was no abnormality of the fetus in the term pregnancy but it seems possible that copper can affect the early growth and development of the embryo. On only 1 of the 8 devices was any great amount of calcium deposited and it is therefore considered unlikely that calcium deposition increases the risk of pregnancy by preventing the release of copper.
在研究的8例妊娠中,2例为妊娠囊小且胚胎停育,与铜丝具有非常高的可检测到的铜X射线发射率(大于90%)的节育器有关。另外2例妊娠在13周和17周终止妊娠时已发生宫内死亡,妊娠产物中的铜含量各不相同。足月妊娠的胎儿没有异常,但铜似乎有可能影响胚胎的早期生长和发育。8个节育器中只有1个有大量钙沉积,因此认为钙沉积不太可能通过阻止铜的释放而增加妊娠风险。