一种用于测定血液和尿液中青霉胺水平的快速、灵敏技术。
A rapid, sensitive technique to assay penicillamine levels in blood and urine.
作者信息
Russell A S, Saetre R, Davis P, Rabenstein D L
出版信息
J Rheumatol. 1979 Jan-Feb;6(1):15-9.
PMID:439105
Abstract
We have used a rapid, sensitive technique to assay penicillamine and its disulphide metabolites in body fluids. Penicillamine in serum is rapidly oxidized and the serum levels of the reduced material found in a pilot study of 10 patients ranged between 0.07 to 0.28 mg%. This technique may prove useful in allowing closer monitoring of therapy with this agent.
摘要
我们采用了一种快速、灵敏的技术来测定体液中的青霉胺及其二硫化物代谢产物。血清中的青霉胺会迅速被氧化，在对10名患者的初步研究中，所发现的还原物质的血清水平在0.07至0.28毫克%之间。这项技术可能在更密切监测该药物的治疗中被证明是有用的。
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