雌激素生物合成机制的研究。3. C19和C18甾体的芳构化立体化学。 - Suppr

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超能文献

Studies on the mechanism of estrogen biosynthesis. 3. The stereochemistry of aromatization of C19 and C18 steroids.

作者信息

Townsley J D, Brodie H J

出版信息

Biochemistry. 1968 Jan;7(1):33-40. doi: 10.1021/bi00841a005.

DOI:10.1021/bi00841a005

PMID:4394749

Abstract

摘要

相似文献

Studies on the mechanism of estrogen biosynthesis. 3. The stereochemistry of aromatization of C19 and C18 steroids.雌激素生物合成机制的研究。3. C19和C18甾体的芳构化立体化学。

Biochemistry. 1968 Jan;7(1):33-40. doi: 10.1021/bi00841a005.

Aromatization of delta-7-C19-steroids to delta-7-estrogens by human placenta in vitro.人胎盘在体外将δ-7-C19-类固醇芳香化为δ-7-雌激素。

Endocrinology. 1968 Nov;83(5):984-91. doi: 10.1210/endo-83-5-984.

Sterochemistry of estrogen biosynthesis.雌激素生物合成的立体化学

Biochemistry. 1969 Nov;8(11):4304-9. doi: 10.1021/bi00839a013.

The twin ion technique for detection of metabolites by gas chromatography-mass spectrometry: intermediates in estrogen biosynthesis.气相色谱-质谱联用检测代谢物的双离子技术：雌激素生物合成的中间体

Anal Biochem. 1973 May;53(1):64-85. doi: 10.1016/0003-2697(73)90408-9.

Oestrogen synthesis from (4- 14 C-1,2- 3 H)testosterone by placental microsomes from baboons.狒狒胎盘微粒体从（4-¹⁴C-1,2-³H）睾酮合成雌激素。

J Endocrinol. 1972 Jan;52(1):137-45. doi: 10.1677/joe.0.0520137.

Studies on the mechanisms of estrogen biosynthesis. VII. 2-beta-hydroxylation of estr-4-ene-3,17-dione in human placenta, in vitro.雌激素生物合成机制的研究。VII. 人胎盘体外对雌甾-4-烯-3,17-二酮的2-β-羟基化作用

Biochim Biophys Acta. 1969;187(2):275-7. doi: 10.1016/0005-2760(69)90039-3.

Studies on the mechanism of estrogen biosynthesis. 8. The development of inhibitors of the enzyme system in human placenta.雌激素生物合成机制的研究。8. 人胎盘酶系统抑制剂的研发。

Endocrinology. 1973 Mar;92(3):866-80. doi: 10.1210/endo-92-3-866.

The aromatization of (7 -3H) androstenedione by human placental mitochondria.人胎盘线粒体对（7 - 3H）雄烯二酮的芳香化作用。

Steroids. 1973 Jul;22(1):123-32. doi: 10.1016/0039-128x(73)90077-9.

Estrogen biosynthesis and 1beta-hydroxylation using C19 and 19-nor steroid precursors.使用C19和19-去甲甾体前体进行雌激素生物合成和1β-羟基化。

Biochim Biophys Acta. 1976 May 27;431(2):326-34. doi: 10.1016/0005-2760(76)90153-3.

Metabolism of C19-steroids by foetal cotyledons from the bovine placenta at term.足月牛胎盘胎儿叶对C19-甾体的代谢

Res Vet Sci. 1969 Sep;10(5):477-9.

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Coupled electron transfer and proton hopping in the final step of CYP19-catalyzed androgen aromatization.CYP19 催化雄激素芳香化反应最后一步中的偶联电子转移和质子跳跃。

Biochemistry. 2012 Apr 10;51(14):3039-49. doi: 10.1021/bi300017p. Epub 2012 Mar 27.

Enzymic aromatization of 6-alkyl-substituted androgens, potent competitive and mechanism-based inhibitors of aromatase.6-烷基取代雄激素的酶促芳香化反应，芳香化酶的强效竞争性和基于机制的抑制剂。

Biochem J. 1998 Jan 1;329 ( Pt 1)(Pt 1):151-6. doi: 10.1042/bj3290151.

Mechanistic studies on C-19 demethylation in oestrogen biosynthesis.雌激素生物合成中C-19去甲基化的机制研究。

Biochem J. 1982 Mar 1;201(3):569-80. doi: 10.1042/bj2010569.

Biogenesis of oestrogens from (14C)testosterone in the mitochondrial fraction of the human placenta.人胎盘线粒体组分中由（14C）睾酮生成雌激素的过程

Biochem J. 1969 Jul;113(4):737-9. doi: 10.1042/bj1130737.

FSH-induced aromatase activity in hamster granulosa cells: effect of estradiol-17 beta in vitro.

Cell Tissue Res. 1987 Oct;250(1):101-4. doi: 10.1007/BF00214660.

Conversion of a 3-desoxysteroid to 3-desoxyestrogen by human placental aromatase.人胎盘芳香化酶将3-脱氧甾体转化为3-脱氧雌激素。

Proc Natl Acad Sci U S A. 1990 Apr;87(8):2999-3003. doi: 10.1073/pnas.87.8.2999.

Structure-function studies of human aromatase by site-directed mutagenesis: kinetic properties of mutants Pro-308----Phe, Tyr-361----Phe, Tyr-361----Leu, and Phe-406----Arg.通过定点诱变对人芳香化酶进行结构-功能研究：突变体Pro-308→Phe、Tyr-361→Phe、Tyr-361→Leu和Phe-406→Arg的动力学特性

Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):410-4. doi: 10.1073/pnas.88.2.410.

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