心脏选择性β-肾上腺素能受体阻滞与冠状动脉循环。
Cardio-selective beta-adrenoceptor blockade and the coronary circulation.
作者信息
Adam K R, Boyles S, Scholfield P C
出版信息
Br J Pharmacol. 1970 Nov;40(3):534-6. doi: 10.1111/j.1476-5381.1970.tb10639.x.
Abstract
After blockade of myocardial, but not coronary vascular beta-adrenoceptors by practolol, cardiac sympathetic stimulation or exogenously administered noradrenaline gave rise to coronary vasoconstriction, possibly due to stimulation of coronary alpha-adrenoceptors.
摘要
在心得宁阻断心肌而非冠状血管的β-肾上腺素能受体后，心脏交感神经刺激或外源性给予去甲肾上腺素会导致冠状动脉收缩，这可能是由于刺激了冠状动脉的α-肾上腺素能受体。
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本文引用的文献
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Sympathetic control of coronary circulation.冠状动脉循环的交感神经控制。
Circ Res. 1967 Feb;20(2):262-71. doi: 10.1161/01.res.20.2.262.
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The effect of "selective" beta-adrenoceptor blocking drugs on the myocardial circulation.“选择性”β-肾上腺素能受体阻断药物对心肌循环的影响。
Br J Pharmacol. 1970 Jun;39(2):296-308. doi: 10.1111/j.1476-5381.1970.tb12893.x.
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Selective blockade of adrenoceptive beta receptors in the heart.心脏中肾上腺素能β受体的选择性阻断。
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Effects of adrenaline and noradrenaline on coronary blood flow before and after beta-adrenergic blockade.肾上腺素和去甲肾上腺素对β-肾上腺素能阻断前后冠状动脉血流的影响。
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