Vladimirov S S, Torkhovskaia T I, Zykova V P, Gerasimova E N
Kardiologiia. 1979 Apr;19(4):73-80.
A significant increase of the relative phosphatidyl serine level, a decrease in the percentage of lipoleic and arachidonic acids, and an increase in the oleic acid level were revealed in blood platelet phospholipids of patients with ischemic heart disease and severe coronary atherosclerosis. In the entire group of patients with ischemic heart disease (with coronary atherosclerosis of various degree), these changes are less marked and only the decrease in the linoleic acid level as compared to that in healthy individuals is significant. It was established that besides these changes in the phospholipid structures, blood platelet aggregation increases when the severity of the atherosclerotic process in the coronary arteries becomes more pronounced.
在患有缺血性心脏病和严重冠状动脉粥样硬化的患者血小板磷脂中，相对磷脂酰丝氨酸水平显著升高，亚油酸和花生四烯酸百分比降低，油酸水平升高。在整个缺血性心脏病患者组（伴有不同程度的冠状动脉粥样硬化）中，这些变化不太明显，与健康个体相比，只有亚油酸水平降低具有显著性。已确定，除了磷脂结构的这些变化外，当冠状动脉粥样硬化过程的严重程度变得更加明显时，血小板聚集增加。
