Myers R C, Sanchez T V, Keiser J A, Mayor G H
Lab Anim Sci. 1979 Feb;29(1):88-93.
Direct photon absorptiometry was used for the in vivo measurement of bone mineral mass in the rabbit tibia. Bone mineral mass in 124 male and female rabbits was correlated (p less than 0.001) with age to 26 weeks and weight to 5.5 kg. Examining reproducibility and repositioning error, three rabbits were measured 12 times each. Bone mineral mass in the three rabbits was: 0.432 +/- 0.020 g/cm2, 0.414 +/- 0.010 g/cm2 and 0.487 +/- 0.037 g/cm2. The greatest coefficients of variance observed for measurements without repositioning and measurements with repositioning were 4.8% and 7.6%, respectively. The technique provided sensitive, reproducible and noninvasive measurement of bone mineral mass without anesthesia or undue restraint.
采用直接光子吸收法对兔胫骨骨矿物质质量进行活体测量。124只雄性和雌性兔的骨矿物质质量与26周龄和5.5千克体重相关（p小于0.001）。为检验重现性和重新定位误差，对3只兔各测量12次。这3只兔的骨矿物质质量分别为：0.432±0.020克/平方厘米、0.414±0.010克/平方厘米和0.487±0.037克/平方厘米。未重新定位测量和重新定位测量观察到的最大变异系数分别为4.8%和7.6%。该技术无需麻醉或过度约束即可对骨矿物质质量进行灵敏、可重复且无创的测量。
