通过同位素交换研究谷氨酰胺合成酶（大肠杆菌W）的底物结合和反应中间体 - Suppr

Suppr

超能文献

Substrate binding and reaction intermediates of glutamine synthetase (Escherichia coli W) as studied by isotope exchanges.

作者信息

Wedler F C, Boyer P D

出版信息

J Biol Chem. 1972 Feb 25;247(4):984-92.

PMID:4400841

Abstract

摘要

相似文献

Substrate binding and reaction intermediates of glutamine synthetase (Escherichia coli W) as studied by isotope exchanges.通过同位素交换研究谷氨酰胺合成酶（大肠杆菌W）的底物结合和反应中间体

J Biol Chem. 1972 Feb 25;247(4):984-92.

Action patterns of feedback modifiers on equilibrium exchanges and applications to glutamine synthetase (Escherichia coli W).反馈调节剂对平衡交换的作用模式及其在谷氨酰胺合成酶（大肠杆菌W）中的应用

J Biol Chem. 1972 Feb 25;247(4):993-1000.

Some effects of adenylylation on the biosynthetic properties of the glutamine synthetase from Escherichia coli.腺苷酰化对大肠杆菌谷氨酰胺合成酶生物合成特性的一些影响。

Biochemistry. 1970 Feb 3;9(3):633-49. doi: 10.1021/bi00805a025.

Cytidine triphosphate synthetase. Covalent intermediates and mechanisms of action.胞苷三磷酸合成酶。共价中间体与作用机制。

Biochemistry. 1971 Aug 31;10(18):3365-71. doi: 10.1021/bi00794a008.

Mechanisms of substrate binding with glutamine synthetase. Equilibrium isotope exchanges with the ovine brain, pea seed, and Escherichia coli enzymes.谷氨酰胺合成酶与底物结合的机制。与绵羊脑、豌豆种子和大肠杆菌酶的平衡同位素交换。

J Biol Chem. 1974 Aug 25;249(16):5080-7.

Some characteristics of the binding of substrates of glutamine synthetase from Escherichia coli.来自大肠杆菌的谷氨酰胺合成酶底物结合的一些特性。

Biochemistry. 1970 Feb 3;9(3):617-32. doi: 10.1021/bi00805a024.

Effects of cobaltous ion on various catalytic parameters and on heterologous subunit interactions of Escherichia coli glutamine synthetase.钴离子对大肠杆菌谷氨酰胺合成酶各种催化参数及异源亚基相互作用的影响。

Arch Biochem Biophys. 1972 Sep;152(1):356-66. doi: 10.1016/0003-9861(72)90225-1.

ENZYMATIC SYNTHESIS OF BETA-AMINOGLUTARAMIC ACID (BETA-GLUTAMINE) BY GLUTAMINE SYNTHETASE: EVIDENCE FOR THE UTILIZATION OF BETA-AMINOGLUTARYLPHOSPHATE.谷氨酰胺合成酶催化β-氨基谷氨酸（β-谷氨酰胺）的酶促合成：利用β-氨基谷氨酰磷酸的证据。

Biochemistry. 1964 Jun;3:824-8. doi: 10.1021/bi00894a017.

Studies of the mechanism of glutamine synthetase utilizing pH-dependent behavior in catalysis and binding.利用谷氨酰胺合成酶在催化和结合过程中pH依赖性行为的机制研究。

J Biol Chem. 1987 Mar 5;262(7):3037-43.

Fluorometric studies of aza-epsilon-adenylylated glutamine synthetase from Escherichia coli.大肠杆菌中氮杂-ε-腺苷酸化谷氨酰胺合成酶的荧光研究。

J Biol Chem. 1981 Jun 25;256(12):6010-6.

引用本文的文献

Bacterial Glutamine Synthetases as a Novel Metabolic Selection Marker to Improve CHO Cell Culture Performance Through Selection Stringency Modulation.细菌谷氨酰胺合成酶作为一种新型代谢选择标记，通过调节选择严格度来改善中国仓鼠卵巢细胞培养性能。

Biotechnol J. 2025 Sep;20(9):e70119. doi: 10.1002/biot.70119.

Cross-linking mass spectrometry reveals structural insights of the glutamine synthetase from Leishmania braziliensis.交联质谱法揭示了巴西利什曼原虫谷氨酰胺合成酶的结构见解。

Mem Inst Oswaldo Cruz. 2022 Jan 10;116:e210209. doi: 10.1590/0074-02760210209. eCollection 2022.

Structural Analysis of Glutamine Synthetase from Helicobacter pylori.幽门螺杆菌谷氨酰胺合成酶的结构分析。

Sci Rep. 2018 Aug 3;8(1):11657. doi: 10.1038/s41598-018-30191-5.

Structures of the Bacillus subtilis glutamine synthetase dodecamer reveal large intersubunit catalytic conformational changes linked to a unique feedback inhibition mechanism.枯草芽孢杆菌谷氨酰胺合成酶十二聚体的结构揭示了与独特反馈抑制机制相关的大亚基间催化构象变化。

J Biol Chem. 2013 Dec 13;288(50):35801-11. doi: 10.1074/jbc.M113.519496. Epub 2013 Oct 24.

Glutamyl phosphate is an activated intermediate in actin crosslinking by actin crosslinking domain (ACD) toxin.谷氨酰磷酸是肌动蛋白交联结构域（ACD）毒素交联肌动蛋白的活化中间产物。

PLoS One. 2012;7(9):e45721. doi: 10.1371/journal.pone.0045721. Epub 2012 Sep 21.

Mechanistic studies of glutamine synthetase from Escherichia coli: kinetic evidence for two reaction intermediates in biosynthetic reaction.大肠杆菌谷氨酰胺合成酶的机制研究：生物合成反应中两个反应中间体的动力学证据

Proc Natl Acad Sci U S A. 1976 Feb;73(2):476-80. doi: 10.1073/pnas.73.2.476.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验