γ-羟基丁酸对雏鸡行为、皮层电活动及交叉伸肌反射的影响。
Effects of gamma-hydroxybutyrate on chick behaviour, electrocortical activity and crossed extensor reflexes.
作者信息
Osuide G
出版信息
Br J Pharmacol. 1972 Apr;44(4):593-604. doi: 10.1111/j.1476-5381.1972.tb07299.x.
Abstract
- Convulsant and anticonvulsant effects of gamma-hydroxybutyrate (GHB) have been studied in chicks.2. When administered alone, GHB produced weak myoclonic seizures accompanied by electrocortical synchrony and spikes.3. GHB was found to protect chicks against leptazol- and picrotoxin-induced seizures. A slight potentiation of strychnine-induced seizures was evident.
摘要
已在雏鸡中研究了γ-羟基丁酸（GHB）的惊厥和抗惊厥作用。
单独给药时，GHB会引发轻微的肌阵挛性癫痫发作，并伴有皮层电同步和尖峰。
发现GHB可保护雏鸡免受戊四氮和印防己毒素诱发的癫痫发作。士的宁诱发的癫痫发作有轻微增强。
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Br J Pharmacol. 1972 Apr;44(4):593-604. doi: 10.1111/j.1476-5381.1972.tb07299.x.
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THE ACTION OF SODIUM 4-HYDROXYBUTYRATE ON SPINAL REFLEXES.4-羟基丁酸钠对脊髓反射的作用
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