Vermorken A J, Weterings P J, Bloemendal H
Mol Biol Rep. 1979 Feb 15;4(4):211-6. doi: 10.1007/BF00777556.
The present study demonstrates that protein biosynthesis can be studied in single isolated human scalp hair follicles. The matrix and the sheath are the main regions where amino acids are built in. Incorporation is linear for at least five hours. The newly synthesized proteins can be separated into a water-soluble, a urea-soluble and a urea-insoluble fraction. Product analysis has been performed on the first two fractions, revealing different protein patterns.
本研究表明,蛋白质生物合成可在单个分离的人类头皮毛囊中进行研究。毛基质和毛鞘是氨基酸掺入的主要区域。掺入至少在五个小时内呈线性。新合成的蛋白质可分为水溶性、尿素溶性和尿素不溶性部分。已对前两个部分进行了产物分析,揭示了不同的蛋白质模式。