Salvati F, Troya C
Minerva Med. 1979 Mar 24;70(14):977-80.
Pelger-Huet's granulocyte abnormality is discussed. This abnormality is characterized by the presence of granuloyctes with a non-segmented nucleus and thick nuclear chromatin gathered in large lumps, in contrast with the "youthful" appearance of the nuclei. In humans, a real Pelger-Huet abnormality with familial character and dominant autosomic transmission is distinguished together with a pseudo-Pelger in which the granulocytes assume cytological features similar to those typical of the constitutional abnormality but whose genesis is closely correlated to the disease of which these are an epiphenomenon.
本文讨论了Pelger-Huet粒细胞异常。这种异常的特征是存在细胞核不分叶且核染色质粗大聚集呈大块状的粒细胞，这与细胞核的“幼稚”外观形成对比。在人类中，可区分出具有家族特征和常染色体显性遗传的真正的Pelger-Huet异常，以及一种假性Pelger-Huet异常，其中粒细胞呈现出与体质性异常典型特征相似的细胞学特征，但其发生与作为这些特征表象的疾病密切相关。
