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30岁之前的单纯性青光眼。

Simple glaucoma before the age of 30 years.

作者信息

Leydhecker W

出版信息

Ophthalmologica. 1979;178(1-2):32-6. doi: 10.1159/000308803.

DOI:10.1159/000308803
PMID:440698
Abstract

'Juvenile glaucoma' is a meaningless term which should not be used. Glaucoma in young subjects can be hydrophthalmus, secondary or simple glaucoma. In this paper, early simple glaucoma is described in 15 patients (8 males, 7 females) below the age of 30 years, starting in some subjects already at 8 years of age. Inheritance was dominant in 6 patients. Anticipation could be shown in 2 pedigrees through 4 and 5 generations, respectively. The course of the disease was severe in 8 patients, with intraocular pressures over 40 mm Hg and/or heavy functional loss. There were usually no subjective symptoms. The chamber angles were gonioscopically normal in all patients. Miotics were effective but did not normalize the intraocular pressure. Surgical treatment is discussed.

摘要

“青少年青光眼”是一个毫无意义的术语,不应使用。年轻患者的青光眼可以是水眼症、继发性青光眼或原发性青光眼。本文描述了15例30岁以下的早期原发性青光眼患者(8例男性,7例女性),其中一些患者在8岁时就已发病。6例患者为显性遗传。在2个家系中分别通过4代和5代显示出遗传早现现象。8例患者病情严重,眼压超过40毫米汞柱和/或有严重的功能丧失。通常没有主观症状。所有患者的房角在房角镜检查下均正常。缩瞳剂有效,但不能使眼压恢复正常。文中讨论了手术治疗方法。

相似文献

1
Simple glaucoma before the age of 30 years.30岁之前的单纯性青光眼。
Ophthalmologica. 1979;178(1-2):32-6. doi: 10.1159/000308803.
2
Congenital glaucoma due to dominant goniodysgenesis. A new concept of the heredity of glaucoma.由显性前房角发育异常引起的先天性青光眼。青光眼遗传的新概念。
Am J Hum Genet. 1983 Jul;35(4):645-51.
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Hereditary glaucoma: a report of two pedigrees.遗传性青光眼:两个家系的报告。
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[Review of 402 goniotrephinations].[402例前房角切开术回顾]
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[Our experience in the treatment of congenital glaucoma].[我们在先天性青光眼治疗方面的经验]
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引用本文的文献

1
Anticipation, anti-glaucoma drug treatment response and phenotype of a Chinese family with glaucoma caused by the Pro370Leu myocilin mutation.一个因Myocilin基因Pro370Leu突变导致青光眼的中国家系的疾病预期、抗青光眼药物治疗反应及表型
Int J Ophthalmol. 2014 Feb 18;7(1):44-50. doi: 10.3980/j.issn.2222-3959.2014.01.08. eCollection 2014.
2
Clinical correlates to the goniodysgensis among juvenile-onset primary open-angle glaucoma patients.青少年起病的原发性开角型青光眼患者的房角发育不良的临床相关性。
Graefes Arch Clin Exp Ophthalmol. 2013 Jun;251(6):1571-6. doi: 10.1007/s00417-013-2262-2. Epub 2013 Jan 29.
3
Genetic screening in a large family with juvenile onset primary open angle glaucoma.
对一个患有青少年型原发性开角型青光眼的大家庭进行基因筛查。
Br J Ophthalmol. 2000 Jul;84(7):722-6. doi: 10.1136/bjo.84.7.722.
4
The genetics of primary open angle glaucoma.原发性开角型青光眼的遗传学
Br J Ophthalmol. 1997 May;81(5):409-14. doi: 10.1136/bjo.81.5.409.
5
Autosomal dominant juvenile onset glaucoma affecting six generations in an Edinburgh family.
Br J Ophthalmol. 1986 Sep;70(9):715. doi: 10.1136/bjo.70.9.715.