Conley S B, Shackelford G D, Robson A M
Pediatrics. 1979 Jan;63(1):142-5.
Severe hypercalcemia with decreased renal function, hypertension, and renal calcifications developed in a 14-year-old boy who required prolonged immobilization for multiple fractures. Parathyroid hormone was not detectable in the serum. Urinary calcium excretion was high. Initially, mobilization was impossible and the patient was treated with a high fluid intake, low calcium intake, acidification of the urine, furosemide, and a passive exercise program. Renal function improved and renal calcifications resolved but hypercalcemia did not resolve. After mobilization the serum calcium concentration became normal rapidly. This treatment regimen is suggested for use in patients with immobilization hypercalcemia when mobilization is impossible.
一名14岁男孩因多处骨折需要长期制动，出现了严重高钙血症，伴有肾功能减退、高血压和肾钙化。血清中未检测到甲状旁腺激素。尿钙排泄量很高。起初，患者无法活动，接受了高液体摄入量、低钙摄入量、尿液酸化、呋塞米治疗以及被动运动方案。肾功能得到改善，肾钙化消失，但高钙血症并未缓解。活动后，血清钙浓度迅速恢复正常。对于无法活动的制动性高钙血症患者，建议采用这种治疗方案。
