治疗对钙稳态紊乱时肠道钙吸收速率的影响。
Effects of therapy on rate of absorption of calcium from gut in disorders of calcium homoeostasis.
作者信息
Reeve J, Hesp R, Veall N
出版信息
Br Med J. 1974 Aug 3;3(5926):310-3. doi: 10.1136/bmj.3.5926.310.
Abstract
A development of the double-tracer calcium absorption test, in which a function is derived for single-passage entry rate from the gut with time, has been assessed in various disorders of calcium homoeostasis. Single tests are diagnostically useful in calcium malabsorption but because of the wide spectrum of normal values a single test can only moderately enhance the accuracy of the diagnosis of hypercalcaemic states made primarily by other methods. On the other hand serial studies in the same subject can be much more informative because the test is normally highly reproducible if conditions are unchanged. Serial studies play an important part in assessing the efficacy of established methods of treatment in disorders of calcium homoeostasis and should be particularly helpful in studying the effects of new forms of therapy on the absorption process.
摘要
双示踪剂钙吸收试验的一种改进方法已在各种钙稳态紊乱中进行了评估，该方法可得出钙随时间从肠道单通道进入的速率函数。单次测试对钙吸收不良的诊断有用，但由于正常值范围广泛，单次测试只能适度提高主要通过其他方法做出的高钙血症状态诊断的准确性。另一方面，对同一受试者进行系列研究可能更具信息价值，因为如果条件不变，该测试通常具有很高的可重复性。系列研究在评估钙稳态紊乱既定治疗方法的疗效方面起着重要作用，并且在研究新治疗形式对吸收过程的影响时应该特别有帮助。
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