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[麻醉医生与抗心律失常药物(不包括β受体阻滞剂)的血流动力学效应]

[The anesthesiologist and the hemodynamic effect of anti-arrhythmic agents (excluding beta blockers)].

作者信息

Bui-Xuan B

出版信息

Ann Anesthesiol Fr. 1979;20(5):397-405.

PMID:44136
Abstract

On the basis of a haemodynamic study involving the intravenous administration of disopyramide, a review is undertaken of the haemodynamic action of various anti-arrhythmics likely to be used pre- or peroperatively by the anaesthetist. All anti-arrhythmic agents have possible haemodynamic properties which may prove troublesome for the anaesthetist: --all (with the possible exception of bretylium tosylate) have negative inotropic properties; --all (with the exception of disopyramide) decrease peripheral resistance. These effects are as a rule slight in the healthy subject but may give rise to difficulties during anaesthesia of a patient with a damaged myocardium.

摘要

基于一项涉及静脉注射丙吡胺的血流动力学研究,对麻醉医生可能在术前或术中使用的各种抗心律失常药物的血流动力学作用进行了综述。所有抗心律失常药物都可能具有血流动力学特性,这可能给麻醉医生带来麻烦:——所有药物(可能除了甲苯磺酸溴苄铵)都有负性肌力作用;——所有药物(除丙吡胺外)都会降低外周阻力。通常情况下,这些作用在健康受试者中较为轻微,但在心肌受损患者的麻醉过程中可能会引发问题。

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